Pharmacological activation of KCa3. 1/KCa2. 3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs

M Damkjaer, G Nielsen, S Bodendiek… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE In rodents, the endothelial KCa channels, KCa3.1 and
KCa2.3, have been shown to play a crucial role in initiating endothelium‐derived …

An Hfq-like protein in archaea: crystal structure and functional characterization of the Sm protein from Methanococcus jannaschii

JS Nielsen, A Bøggild, CBF Andersen, G Nielsen… - Rna, 2007 - rnajournal.cshlp.org
The Sm and Sm-like proteins are conserved in all three domains of life and have emerged
as important players in many different RNA-processing reactions. Their proposed role is to …

[HTML][HTML] A Role for the RNA Chaperone Hfq in Controlling Adherent-Invasive Escherichia coli Colonization and Virulence

KT Simonsen, G Nielsen, JV Bjerrum, T Kruse… - PloS one, 2011 - journals.plos.org
Adherent-invasive Escherichia coli (AIEC) has been linked with the onset and perpetuation
of inflammatory bowel diseases. The AIEC strain LF82 was originally isolated from an ileal …

[BOOK][B] Kommenteret straffelov: Almindelig del

V Greve, A Jensen, GT Nielsen - 1999 - samples.pubhub.dk
Denne kommenterede udgave af straffeloven er bestemt dels til brug for praktiserende jurister,
dels som en del af grundlaget for undervisningen i strafferet ved de højere læreanstalter. …

Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium …

…, L Beck, E Boedtkjer, MW Misfeldt, G Nielsen… - … of Pharmacology and …, 2011 - ASPET
This study was designed to investigate whether calcium-activated potassium channels of
small (SK Ca or K Ca 2) and intermediate (IK Ca or K Ca 3.1) conductance activated by 6,7-…

Activation of endothelial and epithelial KCa2.3 calcium‐activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles

C Kroigaard, T Dalsgaard, G Nielsen… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE Small (K Ca 2) and intermediate (K Ca 3.1) conductance
calcium‐activated potassium channels (K Ca ) may contribute to both epithelium‐ and …

Improvement of endothelium‐dependent vasodilations by SKA‐31 and SKA‐20, activators of small‐ and intermediate‐conductance Ca2+‐activated K+‐channels

AL Hasenau, G Nielsen, C Morisseau… - Acta …, 2011 - Wiley Online Library
Aim: Endothelial membrane hyperpolarization mediated by KCa3.1 and KCa2.3 channels
has been demonstrated to initiate endothelium‐derived hyperpolarizing factor (EDHF)‐type …

Alterations of N‐3 Polyunsaturated Fatty Acid‐Activated K2P Channels in Hypoxia‐Induced Pulmonary Hypertension

G Nielsen, C Wandall‐Frostholm… - Basic & clinical …, 2013 - Wiley Online Library
Polyunsaturated fatty acid (PUFA)‐activated two‐pore domain potassium channels (K 2P )
have been proposed to be expressed in the pulmonary vasculature. However, their …

Amplification of EDHF‐type vasodilatations in TRPC1‐deficient mice

K Schmidt, G Dubrovska, G Nielsen… - British journal of …, 2010 - Wiley Online Library
BACKGROUND AND PURPOSE TRPC1 channels are expressed in the vasculature and
are putative candidates for intracellular Ca 2+ handling. However, little is known about their …

[HTML][HTML] Pulmonary Hypertension in Wild Type Mice and Animals with Genetic Deficit in KCa2.3 and KCa3.1 Channels

…, LM Skaarup, V Sadda, G Nielsen… - PLoS …, 2014 - journals.plos.org
Objective In vascular biology, endothelial K Ca 2.3 and K Ca 3.1 channels contribute to arterial
blood pressure regulation by producing membrane hyperpolarization and smooth muscle …