Translation and protein synthesis: macrolides
L Katz, GW Ashley - Chemical reviews, 2005 - ACS Publications
The term “macrolide” was originally proposed by RB Woodward in 1957 as an abbreviation
of macrolactone glycoside antibiotics, a class of natural products composed of macrocyclic …
of macrolactone glycoside antibiotics, a class of natural products composed of macrocyclic …
Classification of large-scale subaqueous bedforms; a new look at an old problem
GM Ashley - Journal of Sedimentary Research, 1990 - pubs.geoscienceworld.org
… The symposium was convened by GM Ashley and RD Kreisa and sponsored by the SEPM
Bedforrns and Bedding Structures Research Group. Most of the ideas presented herein …
Bedforrns and Bedding Structures Research Group. Most of the ideas presented herein …
Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products
…, H Fu, M Betlach, M Betlach, G Ashley - Proceedings of the …, 1999 - National Acad Sciences
The structures of complex polyketide natural products, such as erythromycin, are programmed
by multifunctional polyketide synthases (PKSs) that contain modular arrangements of …
by multifunctional polyketide synthases (PKSs) that contain modular arrangements of …
Processes, bar morphology, and sedimentary structures on braided outwash fans, northeastern Gulf of Alaska
JC Boothroyd, GM Ashley - 1975 - archives.datapages.com
The Scott and Yana outwash fans on the northeastern Gulf of Alaska exhibit a succession of
facies from glacier terminus to tidewater that are each characterized by differences of …
facies from glacier terminus to tidewater that are each characterized by differences of …
Hydrogel drug delivery system with predictable and tunable drug release and degradation rates
GW Ashley, J Henise, R Reid… - Proceedings of the …, 2013 - National Acad Sciences
Many drugs and drug candidates are suboptimal because of short duration of action. For
example, peptides and proteins often have serum half-lives of only minutes to hours. One …
example, peptides and proteins often have serum half-lives of only minutes to hours. One …
Long-term stabilization of maleimide–thiol conjugates
…, R Reid, L Robinson, GW Ashley… - Bioconjugate …, 2015 - ACS Publications
Michael-addition of a thiol to a maleimide is commonly used for bioconjugation of drugs to
macromolecules. Indeed, both current FDA-approved antibody–drug conjugates…
macromolecules. Indeed, both current FDA-approved antibody–drug conjugates…
A model of structure and catalysis for ketoreductase domains in modular polyketide synthases
R Reid, M Piagentini, E Rodriguez, G Ashley… - Biochemistry, 2003 - ACS Publications
A putative catalytic triad consisting of tyrosine, serine, and lysine residues was identified in
the ketoreductase (KR) domains of modular polyketide synthases (PKSs) based on homology …
the ketoreductase (KR) domains of modular polyketide synthases (PKSs) based on homology …
Late Pliocene Homo and Hominid Land Use from Western Olduvai Gorge, Tanzania
…, RL Hay, CC Swisher, IG Stanistreet, GM Ashley… - Science, 2003 - science.org
Excavation in the previously little-explored western portion of Olduvai Gorge indicates that
hominid land use of the eastern paleobasin extended at least episodically to the west. Finds …
hominid land use of the eastern paleobasin extended at least episodically to the west. Finds …
Rhythmic sedimentation in glacial lake Hitchcock, Massachusetts-Connecticut
GM Ashley - 1975 - archives.datapages.com
… Stream water would enter the lake and flolv at a level determined l~g the positive or negative
difference 11et\\~ee11 stream density and lake density. "lnterflo\v" is the term t~setl to describe …
difference 11et\\~ee11 stream density and lake density. "lnterflo\v" is the term t~setl to describe …
Deposition of climbing‐ripple beds: a flume simulation
GM Ashley, JB Southard, JONC BooTHRoyD - Sedimentology, 1982 - Wiley Online Library
Thirteen runs were made in a small recirculating flume to simulate the deposition of the
climbing‐ripple sequences commonly present in fine‐grained facies of fluvial and deltaic deposits…
climbing‐ripple sequences commonly present in fine‐grained facies of fluvial and deltaic deposits…