The sympathomimetic actions of l-ephedrine and d-pseudoephedrine: direct receptor activation or norepinephrine release?
S Kobayashi, M Endou, F Sakuraya… - Anesthesia & …, 2003 - journals.lww.com
IMPLICATIONS: The indirectly sympathomimetic property of l-ephedrine may be one of the
mechanisms to explain why ephedrine is preferred over α-adrenergic agonists as a …
mechanisms to explain why ephedrine is preferred over α-adrenergic agonists as a …
Temporal changes in pulmonary expression of key procoagulant molecules in rabbits with endotoxin-induced acute lung injury: elevated expression levels of protease …
…, I Sakuma, S Kobayashi, F Sakuraya… - Thrombosis and …, 2004 - thieme-connect.com
Recently a new concept has emerged implicating thrombin signaling as the “bridge” that
connects tissue damage to hemostatic and inflammatory responses. In view of this concept, we …
connects tissue damage to hemostatic and inflammatory responses. In view of this concept, we …
Hemodynamic significance of histamine synthesis and histamine H1- and H2-receptor gene expression during endotoxemia
N Matsuda, Y Hattori, F Sakuraya, M Kobayashi… - Naunyn-Schmiedeberg's …, 2002 - Springer
The hypothesis that endotoxemia may modify histamine synthesis or histamine receptor
expression and that these changes may contribute to cardiovascular dysfunction was tested in …
expression and that these changes may contribute to cardiovascular dysfunction was tested in …
Comparison of the analgesic efficacy of ultrasound‐guided rectus sheath block and local anesthetic infiltration for laparoscopic percutaneous extraperitoneal closure …
Y Uchinami, F Sakuraya, N Tanaka… - Pediatric …, 2017 - Wiley Online Library
Background Ultrasound‐guided rectus sheath block and local anesthetic infiltration are the
standard options to improve postoperative pain for children undergoing surgery with a …
standard options to improve postoperative pain for children undergoing surgery with a …
Pharmacological significance of the blocking action of the intravenous general anesthetic propofol on the slow component of cardiac delayed rectifier K+ current
N Hatakeyama, F Sakuraya, N Matsuda… - Journal of …, 2009 - Elsevier
Propofol is a widely used intravenous general anesthetic. The negative inotropic effect of
propofol has been best explained by inhibition of the L-type Ca 2+ current (I Ca ). Using guinea-…
propofol has been best explained by inhibition of the L-type Ca 2+ current (I Ca ). Using guinea-…
[HTML][HTML] Differential expression, time course and distribution of four PARs in rats with endotoxin-induced acute lung injury
S Jesmin, S Gando, S Zaedi, F Sakuraya - Inflammation, 2007 - Springer
The hypothesis that the expression of protease-activated receptors (PARs) protein is regulated
at the level of transcription and that PAR isoforms, PAR-1, PAR-2, PAR-3, and PAR-4, in …
at the level of transcription and that PAR isoforms, PAR-1, PAR-2, PAR-3, and PAR-4, in …
Normalization by edaravone, a free radical scavenger, of irradiation-reduced endothelial nitric oxide synthase expression
XH Zhang, N Matsuda, S Jesmin, F Sakuraya… - European journal of …, 2003 - Elsevier
We investigated the therapeutic effect of edaravone, a free radical scavenger, on alterations
in endothelium-dependent relaxation and endothelial nitric oxide synthase (eNOS) …
in endothelium-dependent relaxation and endothelial nitric oxide synthase (eNOS) …
Chronological expression of PAR isoforms in acute liver injury and its amelioration by PAR2 blockade in a rat model of sepsis
…, S Gando, S Zaedi, F Sakuraya - Thrombosis and …, 2006 - thieme-connect.com
The liver can be injured and its functions altered by activation of the coagulation and inflammatory
processes in sepsis. The objective of the present study was to investigate the pattern …
processes in sepsis. The objective of the present study was to investigate the pattern …
Effects of Ca2+ sensitizers on contraction,[Ca2+] i transient and myofilament Ca2+ sensitivity in diabetic rat myocardium: potential usefulness as inotropic agents
T Ishitani, Y Hattori, F Sakuraya, H Onozuka… - … of Pharmacology and …, 2001 - ASPET
The purpose of the present study was to investigate the effects of Ca 2+ sensitizers EMD
57033, MCI-154, and EGIS-9377 in cardiac preparations from streptozotocin-induced diabetic …
57033, MCI-154, and EGIS-9377 in cardiac preparations from streptozotocin-induced diabetic …
Protein kinase C modulation of the regulation of sarcoplasmic reticular function by protein kinase A‐mediated phospholamban phosphorylation in diabetic rats
S Watanuki, N Matsuda, F Sakuraya… - British journal of …, 2004 - Wiley Online Library
The goal of this study was to elucidate the possible mechanisms by which protein kinase A (PKA)‐mediated
regulation of the sarcoplasmic reticulum (SR) via phospholambin protein …
regulation of the sarcoplasmic reticulum (SR) via phospholambin protein …