Low Whole-Blood S-Adenosylmethionine and Correlation Between 5-Methyltetrahydrofolate and Homocysteine in Coronary Artery Disease

FMT Loehrer, CP Angst, WE Haefeli… - … , and vascular biology, 1996 - Am Heart Assoc
Mild elevation of plasma homocysteine is an independent risk factor for vascular disease.
We studied the role of 5-methyltetrahydrofolate (5-MTHF), the folate form directly involved in …

Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease

FMT Loehrer, M Tschöpl, CP Angst, P Litynski, K Jäger… - Atherosclerosis, 2001 - Elsevier
Altered homocysteine metabolism associated with peripheral arterial occlusive disease (PAOD)
may lead to impairment of vital methylation reactions through accumulation of S-…

Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans

FMT Loehrer, R Schwab, CP Angst, WE Haefeli… - … of Pharmacology and …, 1997 - ASPET
Elevated plasma homocysteine concentration is an independent risk factor for vascular disease
in humans. In addition to nutritional and genetic factors, an interruption of the coordinate …

Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans

FMT Loehrer, WE Haefeli, CP Angst, G Browne… - Clinical …, 1996 - portlandpress.com
1. Elevated plasma homocysteine concentration, either in the fasting state or after methionine
loading, is an independent risk factor for vascular disease in man. Methionine loading has …

Evidence for disturbed S-adenosylmethionine: S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?

FM Loehrer, CP Angst, FP Brunner… - … official publication of …, 1998 - academic.oup.com
BACKGROUND: Elevated homocysteine concentrations have been associated with premature
arteriosclerosis and with impairment of key methylation reactions through accumulation of …

Analysis of shared heritability in common disorders of the brain

…, B Muller-Myhsok, S Schreiber, V Salomaa, E Loehrer… - Science, 2018 - science.org
INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

Plasma S-adenosylhomocysteine: a potential risk marker for cerebral venous thrombosis

VP Bharatkumar, KJ Rudreshkumar, D Nagaraja… - Clinica Chimica …, 2016 - Elsevier
Background Despite a plethora of studies suggesting that hyperhomocysteinemia is associated
with an increased risk for arterial and venous thrombosis, there is paucity of data on the …

Acknowledgement to Reviewers of Risks in 2017

…, D Sornette, M Bee, A Kuznetsov, S Spaeter-Loehrer… - 2018 - search.proquest.com
Peer review is an essential part in the publication process, ensuring that Risks maintains high
quality standards for its published papers. In 2017, a total of 62 papers were published in …

Single‐Dose Pharmacokinetics of the CCR9 Receptor Antagonist Vercirnon in Healthy US and Japanese Subjects

LJ Haberer, K Hacquoil, H Ino… - Clinical …, 2013 - Wiley Online Library
… The authors wish to thank Robert Blum and the staff at Buffalo Clinical Research Center (BCRC),
Buffalo, NY for their support with the conduction of the US study and Franziska Loehrer, …

[HTML][HTML] Analysis of shared heritability in common disorders of the brain

Brainstorm Consortium - Science (New York, NY), 2018 - ncbi.nlm.nih.gov
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share
symptoms, provoking debate about their etiologic overlap. We quantified the genetic …