Temporal patterns of the cerebral inflammatory response in the rat lithium–pilocarpine model of temporal lobe epilepsy
B Voutsinos-Porche, E Koning, H Kaplan… - Neurobiology of …, 2004 - Elsevier
To better understand the role of inflammatory responses in temporal lobe epilepsy, we
characterized Interleukin1-β (IL1-β), Nuclear Factor-κB (NF-κB), and Cyclooxygenase-2 (COX-2) …
characterized Interleukin1-β (IL1-β), Nuclear Factor-κB (NF-κB), and Cyclooxygenase-2 (COX-2) …
Neuroprotective properties of topiramate in the lithium-pilocarpine model of epilepsy
MA Rigoulot, E Koning, A Ferrandon, A Nehlig - Journal of Pharmacology …, 2004 - ASPET
The lithium-pilocarpine model reproduces the main characteristics of human temporal lobe
epilepsy. After status epilepticus (SE), rats exhibit a latent seizure-free phase characterized …
epilepsy. After status epilepticus (SE), rats exhibit a latent seizure-free phase characterized …
Selective reorganization of GABAergic transmission in neonatal ventral hippocampal-lesioned rats
J François, A Ferrandon, E Koning… - International Journal …, 2009 - academic.oup.com
Post-mortem studies suggested a disturbance of the GABAergic system in schizophrenia.
Neonatal ventral hippocampal-lesioned (NVHL) rats were used as a neurodevelopmental …
Neonatal ventral hippocampal-lesioned (NVHL) rats were used as a neurodevelopmental …
Anxiety and locomotion in Genetic Absence Epilepsy Rats from Strasbourg (GAERS): inclusion of Wistar rats as a second control
…, JB Faure, B Cosquer, E Koning… - …, 2014 - Wiley Online Library
Objective The Genetic Absence Epilepsy Rats from Strasbourg ( GAERS) is a genetic model,
derived from Wistar rats by selective breeding. In all previous studies, GAERS were …
derived from Wistar rats by selective breeding. In all previous studies, GAERS were …
Long‐term pregabalin treatment protects basal cortices and delays the occurrence of spontaneous seizures in the lithium‐pilocarpine model in the rat
V André, MA Rigoulot, E Koning, A Ferrandon… - …, 2003 - Wiley Online Library
Purpose: To determine whether a pharmacologic treatment could delay or prevent the
epileptogenesis induced by status epilepticus (SE) through the protection of some brain areas, we …
epileptogenesis induced by status epilepticus (SE) through the protection of some brain areas, we …
A comprehensive behavioral evaluation in the lithium–pilocarpine model in rats: effects of carisbamate administration during status epilepticus
…, B Cosquer, A Ferrandon, K Geiger, E Koning… - …, 2013 - Wiley Online Library
Purpose Administration of carisbamate during status epilepticus ( SE ) prevents the occurrence
of motor seizures in the lithium–pilocarpine model and leads in a subpopulation of rats to …
of motor seizures in the lithium–pilocarpine model and leads in a subpopulation of rats to …
Ketogenic diet exhibits neuroprotective effects in hippocampus but fails to prevent epileptogenesis in the lithium‐pilocarpine model of mesial temporal lobe epilepsy in …
B Linard, A Ferrandon, E Koning, A Nehlig, E Raffo - Epilepsia, 2010 - Wiley Online Library
Purpose: Although the number of antiepileptic drugs (AEDs) is increasing, none displays
neuroprotective or antiepileptogenic properties that could prevent status epilepticus (SE)–…
neuroprotective or antiepileptogenic properties that could prevent status epilepticus (SE)–…
Attention and executive functions in a rat model of chronic epilepsy
…, B Cosquer, A Ferrandon, K Herbeaux, E Koning… - …, 2014 - Wiley Online Library
Objective Temporal lobe epilepsy is a relatively frequent, invalidating, and often refractory
neurologic disorder. It is associated with cognitive impairments that affect memory and …
neurologic disorder. It is associated with cognitive impairments that affect memory and …
Prolonged low‐dose caffeine exposure protects against hippocampal damage but not against the occurrence of epilepsy in the lithium‐pilocarpine model in the rat
MA Rigoulot, C Leroy, E Koning, A Ferrandon… - …, 2003 - Wiley Online Library
Purpose: Acute caffeine exposure has proconvulsant effects and worsens epileptic and
ischemic neuronal damage. Surprisingly, prolonged caffeine exposure decreases the …
ischemic neuronal damage. Surprisingly, prolonged caffeine exposure decreases the …
The combination of topiramate and diazepam is partially neuroprotective in the hippocampus but not antiepileptogenic in the lithium-pilocarpine model of temporal …
J François, E Koning, A Ferrandon, A Nehlig - Epilepsy research, 2006 - Elsevier
Lithium-pilocarpine induces status epilepticus (SE), leading to extensive damage and
spontaneous recurrent seizures (SRS). Neuroprotective and antiepileptogenic effects of …
spontaneous recurrent seizures (SRS). Neuroprotective and antiepileptogenic effects of …