Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has been postulated as an
adjuvant analgesic for preventing remifentanil-induced hyperalgesia after surgery. This …

We evaluated the role of σ 1 receptors on capsaicin-induced mechanical hypersensitivity
and on nociceptive pain induced by punctate mechanical stimuli, using wild-type and σ 1 …

We evaluated the effect of low doses of systemically administered tetrodotoxin (TTX) on the
development and expression of neuropathic pain induced by paclitaxel in mice. Treatment …

We evaluated the effects of phenytoin (DPH) on the affinity for sigma‐1 (σ 1 ) receptors of
agonist or antagonist σ 1 ligands in guinea pig brain. Heterologous competition experiments …

Rationale We evaluated the effects of haloperidol and its metabolites on capsaicin-induced
mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate …

We evaluated the effect of haloperidol (HP) and its metabolites on [ 3 H](+)‐pentazocine
binding to σ 1 receptors in SH‐SY5Y human neuroblastoma cells and guinea pig brain P 1 , P 2 …

1 We evaluated the effects of the iev administration of different K + channel blockers (gliquidone,
4‐aminopyridine and tetraethylammonium) and an opener of K + channels (cromakalim…

The possibility that calcium channel blockers might produce antinociception and increase
morphine analgesia was examined using the acetic acid writhing test in mice. Subcutaneous …

1 The actions of the trivalent cation, gadolinium (Gd 3+ ), were studied on frog isolated
neuromuscular preparations by conventional electrophysiological techniques. 2 Gd 3+ (450 μm) …

The modulation by K + channel-acting drugs of the antinociceptive effect of several 5-HT 1A
receptor agonists was examined with the hot plate test in mice. All the 5-HT 1A receptor …