5-Hydroxytryptamine (5-HT) can produce both vasoconstrictor and vasorelaxant effects in
human coronary arteries and the response to 5-HT can be influenced by the presence of …

We wanted to study the expression of P2-receptors at the mRNA-level in the heart and if it is
affected by congestive heart failure (CHF). To quantify the P2 receptor mRNA-expression we …

The present study was designed to evaluate the relative contribution of the different contractile
P2 receptors in endothelium-denuded human coronary arteries by use of extracellular …

Intravenous iron preparations have shown benefit in patients with chronic heart failure (CHF)
and iron deficiency. Iron isomaltoside 1000 (Monofer) is a novel intravenous iron …

Patients in the latest stages of heart failure are severely compromised, with poor quality of
life and frequent hospitalizations. Heart transplantation and left ventricular assist device …

Although a cornerstone in the treatment of heart failure, angiotensin-converting enzyme
inhibitors are under-used, partly due to side effects. If proven at least similarly efficacious to …

Background: Angiotensin II (Ang II) is a potent vasoconstrictor and a deleterious factor in
cardiovascular pathophysiology. Ang II receptor blockers (ARBs) have recently been introduced …

Angiotensin II is a potent vasoconstrictor that is implicated in the pathogenesis of hypertension,
heart failure and atherosclerosis. In the present study, angiotensin II receptor mRNA …

OBJECTIVE: To describe serum concentrations and clearance of sotalol after a massive
overdose. CASE SUMMARY: A 37-year-old white man took 11.2 g of sotalol hydrochloride …

The in vitro effects of angiotensin II (Ang II) in human vessels are not well studied. The
development of specific Ang II-receptor antagonists has made it possible to delineate more …