[PDF][PDF] Deconstructing adipogenesis induced by β3-adrenergic receptor activation with single-cell expression profiling

RB Burl, VD Ramseyer, EA Rondini, R Pique-Regi… - Cell metabolism, 2018 - cell.com
Recruitment of brown/beige adipocytes (BAs) in white adipose tissue (WAT) involves
proliferation and differentiation of adipocyte stem cells (ASCs) in concert with close interactions …

Deconstructing cold-induced brown adipocyte neogenesis in mice

RB Burl, EA Rondini, H Wei, R Pique-Regi… - Elife, 2022 - elifesciences.org
Cold exposure triggers neogenesis in classic interscapular brown adipose tissue (iBAT) that
involves activation of β1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue …

[HTML][HTML] Lipolysis regulates major transcriptional programs in brown adipocytes

LK Markussen, EA Rondini, OS Johansen… - Nature …, 2022 - nature.com
β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both
lipolysis and transcription of thermogenic genes, thereby expanding the capacity for oxidative …

Single cell approaches to address adipose tissue stromal cell heterogeneity

EA Rondini, JG Granneman - Biochemical Journal, 2020 - portlandpress.com
A central function of adipose tissue is in the management of systemic energy homeostasis
that is achieved through the co-ordinated regulation of energy storage and mobilization, …

[HTML][HTML] Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner

EA Rondini, DM Walters, AK Bauer - Particle and fibre toxicology, 2010 - Springer
Background Elevated levels of air pollution are associated with increased risk of lung cancer.
Particulate matter (PM) contains transition metals that may potentiate neoplastic …

[HTML][HTML] Supplementation with galacto-oligosaccharides increases the percentage of NK cells and reduces colitis severity in Smad3-deficient mice

A Gopalakrishnan, JF Clinthorne, EA Rondini… - The Journal of …, 2012 - Elsevier
The gut microbiota plays an essential role in intestinal immunity. Prebiotics, including
galacto-oligosaccharides (GOS), are fermentable fibers that beneficially affect the host by …

[HTML][HTML] REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction.

…, H Im, YK Cho, JK Seong, RB Burl, EA Rondini… - Metabolism, 2022 - Elsevier
Introduction The mobilization and catabolism of lipid energy is a central function of
adipocytes that is under the control of the β-adrenergic signaling pathway, and defects in β-…

Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70

AK Bauer, EA Rondini, KA Hummel… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Toll-like receptor 4 (TLR4) is involved in ozone (O 3 )-induced pulmonary
hyperpermeability and inflammation, although the downstream signaling events are unknown. …

Energy balance modulates colon tumor growth: interactive roles of insulin and estrogen

EA Rondini, AE Harvey, JP Steibel… - Molecular …, 2011 - Wiley Online Library
Obesity increases colorectal cancer (CRC) risk and progression. However, the impact of
obesity on CRC in women is dependent on ovarian hormone status. The purpose of this study …

Novel pharmacological probes reveal ABHD5 as a locus of lipolysis control in white and brown adipocytes

EA Rondini, L Mladenovic-Lucas, WR Roush… - … of Pharmacology and …, 2017 - ASPET
Current knowledge regarding acute regulation of adipocyte lipolysis is largely based on
receptor-mediated activation or inhibition of pathways that influence intracellular levels of cAMP, …