Physicochemical properties, solubility, and protein binding of Δ9 ‐tetrahydrocannabinol

ER Garrett, CA Hunt - Journal of pharmaceutical sciences, 1974 - Wiley Online Library
The rate and extent of glass binding of Δ 9 ‐tetrahydrocannabinol in aqueous solution depend
on the surface area and pretreatment of glass and the concentration of the drug. A total of …

Solvolysis of adenine nucleosides. I. Effects of sugars and adenine substituents on acid solvolyses

ER Garrett, PJ Mehta - Journal of the American Chemical Society, 1972 - ACS Publications
2'C-methyladenosine result in the respective sugar and stable adenine moiety except in the
case of 1-methyladenosine where the resultant 1-methyladenine is more slowly transformed …

Pharmacokinetics of Δ9-tetrahydrocannabinol in dogs

ER Garrett, CA Hunt - Journal of pharmaceutical sciences, 1977 - Elsevier
The pharmacokinetics of intravenously administered 14 C-Δ 9 -tetrahydrocannabinoaln d
derived radiolabgled metabolites were studied in three dogs at two doses each at 0.1 or 0.5 …

Kinetics and mechanisms of the acid degradation of the aldopentoses to furfural

ER Garrett, BH Dvorchik - Journal of pharmaceutical sciences, 1969 - Wiley Online Library
The acid degradation of the aldopentoses to furfural and the degradation of furfural were
followed spectrophotometrically and are first‐order functions of HCI and pentose concentration. …

The Bateman function revisited: a critical reevaluation of the quantitative expressions to characterize concentrations in the one compartment body model as a function …

ER Garrett - Journal of pharmacokinetics and biopharmaceutics, 1994 - Springer
… ~l'his section and many of the others following that are unreferenced were based, in part,
on an unpublished manuscript "Basic Pharmacokinetics" by Edward R. Garrett that was used …

Prediction of stability of drugs and pharmaceutical preparations

ER Garrett - Journal of Pharmaceutical Sciences, 1962 - Elsevier
By EDWARD R. GARRETT o PREDICT is “to tell or declare beforehand, Thetell or prophesy”(190).
In the realms of science, prediction is based on a knowledge of the relations among …

Solvolyses of cytosine and cytidine

ER Garrett, J Tsau - Journal of pharmaceutical sciences, 1972 - Elsevier
It has been confirmed by UV spectrophotometry and TLC that cytosine and cytidine deaminate
to uracil and uridine, respectively, at all pH values. These products slowly degrade further …

Kinetics of hydrolysis of barbituric acid derivatives

ER Garrett, JT Bojarski, GJ Yakatan - Journal of Pharmaceutical Sciences, 1971 - Elsevier
The neutral and alkaline hydrolyses of barbituric acid and some of its substituted derivatives
were followed spectrophotometrically. The rate‐pH profiles for all of the 5,5‐disubstituted …

The Acid-Catalyzed Solvolysis of Pyrimidine Nucleosides1

ER Garrett, JK Seydel, AJ Sharpen - The Journal of Organic …, 1966 - ACS Publications
The kinetics of acid-catalyzed solvolysis of various pyrimidine nucleosides have been studied
at various temperatures and specific acid catalysis was established for all compounds …

Pharmacokinetics and bioavailabilities of hymecromone in human volunteers

ER Garrett, J Venitz, K Eberst… - Biopharmaceutics & drug …, 1993 - Wiley Online Library
Specific and ultrasensitive reverse‐phase HPLC assays of the choleretic and biliary
antispasmodic hymecromone (down to 0.05 ng ml −1 ) and its glucuronide, using fluorimetric …