User profiles for Edward Perez-Reyes
Edward Perez-ReyesProfessor of Pharmacology, University of Virginia Verified email at virginia.edu Cited by 25388 |
Molecular physiology of low-voltage-activated t-type calcium channels
E Perez-Reyes - Physiological reviews, 2003 - journals.physiology.org
T-type Ca 2+ channels were originally called low-voltage-activated (LVA) channels because
they can be activated by small depolarizations of the plasma membrane. In many neurons …
they can be activated by small depolarizations of the plasma membrane. In many neurons …
International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
WA Catterall, E Perez-Reyes, TP Snutch… - Pharmacological …, 2005 - ASPET
The family of voltage-gated calcium channels serves as the key transducers of cell surface
membrane potential changes into local intracellular calcium transients that initiate many …
membrane potential changes into local intracellular calcium transients that initiate many …
[PDF][PDF] Nomenclature of voltage-gated calcium channels
…, MM Harpold, F Hofmann, Y Mori, E Perez-Reyes… - Neuron, 2000 - cell.com
As new Ca2+ channel genes are cloned, it is apparent that these two alphabetical nomenclatures
will overlap at α1L, which may not mediate an L-type Ca2+ current and Voltage-gated …
will overlap at α1L, which may not mediate an L-type Ca2+ current and Voltage-gated …
Molecular characterization of a neuronal low-voltage-activated T-type calcium channel
E Perez-Reyes, LL Cribbs, A Daud, AE Lacerda… - Nature, 1998 - nature.com
The molecular diversity of voltage-activated calcium channels was established by studies
showing that channels could be distinguished by their voltage-dependence, deactivation and …
showing that channels could be distinguished by their voltage-dependence, deactivation and …
Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels
…, JH Lee, A Daud, E Perez-Reyes… - Journal of …, 1999 - Soc Neuroscience
Low voltage-activated (T-type) calcium currents are observed in many central and
peripheral neurons and display distinct physiological and functional properties. Using in situ …
peripheral neurons and display distinct physiological and functional properties. Using in situ …
Cloning and Characterization of α1H From Human Heart, a Member of the T-Type Ca2+ Channel Gene Family
…, M Fox, M Rees, E Perez-Reyes - Circulation …, 1998 - Am Heart Assoc
Voltage-activated Ca 2+ channels exist as multigene families that share common structural
features. Different Ca 2+ channels are distinguished by their electrophysiology and …
features. Different Ca 2+ channels are distinguished by their electrophysiology and …
[HTML][HTML] Nickel block of three cloned T-type calcium channels: low concentrations selectively block α1H
JH Lee, JC Gomora, LL Cribbs, E Perez-Reyes - Biophysical journal, 1999 - cell.com
Nickel has been proposed to be a selective blocker of low-voltage-activated, T-type calcium
channels. However, studies on cloned high-voltage-activated Ca 2+ channels indicated that …
channels. However, studies on cloned high-voltage-activated Ca 2+ channels indicated that …
Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family
…, U Klöckner, T Schneider, E Perez-Reyes - Journal of …, 1999 - Soc Neuroscience
Low voltage-activated Ca 2+ channels play important roles in pacing neuronal firing and
producing network oscillations, such as those that occur during sleep and epilepsy. Here we …
producing network oscillations, such as those that occur during sleep and epilepsy. Here we …
The concise guide to pharmacology 2021/22: Ion channels
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …
[HTML][HTML] Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel.
The skeletal muscle dihydropyridine receptor/Ca2+ channel is composed of five protein
components (alpha 1, alpha 2 delta, beta, and gamma). Only two such components, alpha 1 and …
components (alpha 1, alpha 2 delta, beta, and gamma). Only two such components, alpha 1 and …