During the last decade, experimental research has demonstrated a prominent role of glial
cells, activated in brain by various injuries, in the mechanisms of seizure precipitation and …

Over the past decade, an increasing number of observations indicate that activation of
inflammatory processes occurs in variety of focal epilepsies. Understanding the feature and …

Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs. …

Leakage of the blood–brain barrier (BBB) is associated with various neurological disorders,
including temporal lobe epilepsy (TLE). However, it is not known whether alterations of the …

Accurate pathological diagnosis is crucial for optimal management of patients with cancer.
For the approximately 100 known tumour types of the central nervous system, standardization …

Background Detailed neuropathological information on the structural brain lesions underlying
seizures is valuable for understanding drug-resistant focal epilepsy. Methods We report …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets multiple
organs and causes severe coagulopathy. Histopathological organ changes might not only …

Brain inflammation is a major factor in epilepsy, but the impact of specific inflammatory mediators
on neuronal excitability is incompletely understood. Using models of acute and chronic …

Hippocampal sclerosis ( HS ) is the most frequent histopathology encountered in patients
with drug‐resistant temporal lobe epilepsy ( TLE ). Over the past decades, various attempts …

Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly
aggressive, poorly differentiated embryonal tumors occurring predominantly in young children …