User profiles for David Fulton

David C. Fulton

US Geological Survey, Minnesota Cooperative Fish & Wildlife Research Unit, University of …
Verified email at umn.edu
Cited by 4258

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

D Fulton, JP Gratton, TJ McCabe, J Fontana, Y Fujio… - Nature, 1999 - nature.com
Endothelial nitric oxide synthase (eNOS) is the nitric oxide synthase isoform responsible for
maintaining systemic blood pressure, vascular remodelling and angiogenesis 1 , 2 , 3 , 4 . …

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

Y Kureishi, Z Luo, I Shiojima, A Bialik, D Fulton… - Nature medicine, 2000 - nature.com
Recent studies suggest that statins can function to protect the vasculature in a manner that
is independent of their lipid-lowering activity. We show here that statins rapidly activate the …

The treatment of Kawasaki syndrome with intravenous gamma globulin

…, JW Wiggins, RV Hicks, DR Fulton… - … England Journal of …, 1986 - Mass Medical Soc
We compared the efficacy of intravenous gamma globulin plus aspirin with that of aspirin
alone in reducing the frequency of coronary-artery abnormalities in children with acute …

[HTML][HTML] A single intravenous infusion of gamma globulin as compared with four infusions in the treatment of acute Kawasaki syndrome

…, SD Colan, CE Duffy, DR Fulton… - New England journal …, 1991 - Mass Medical Soc
Background. Treatment of acute Kawasaki syndrome with a four-day course of intravenous
gamma globulin, together with aspirin, has been demonstrated to be safe and effective in …

Wildlife value orientations: A conceptual and measurement approach

DC Fulton, MJ Manfredo, J Lipscomb - Human dimensions of …, 1996 - Taylor & Francis
This paper develops a conceptual framework for studying human values toward wildlife. A
measurement instrument for assessing basic wildlife beliefs and wildlife value orientations …

[HTML][HTML] Prophylactic administration of respiratory syncytial virus immune globulin to high-risk infants and young children

…, J Arrobio, HC Meissner, DR Fulton… - … England Journal of …, 1993 - Mass Medical Soc
Background Infants with cardiac disease or prematurity are at risk for severe illness caused
by respiratory syncytial virus. Immune globulin with a high titer of antibodies against …

[HTML][HTML] Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

A Papapetropoulos, D Fulton, K Mahboubi… - Journal of Biological …, 2000 - ASBMB
A productive angiogenic response must couple to the survival machinery of endothelial cells
to preserve the integrity of newly formed vessels. Angiopoietin-1 (Ang-1) is an endothelium-…

Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase–Akt pathway in human endothelial cells

…, D Sinha, KS Russell, M Collinge, D Fulton… - Circulation …, 2000 - Am Heart Assoc
17β-Estradiol (E 2 ) is a rapid activator of endothelial nitric oxide synthase (eNOS). The product
of this activation event, NO, is a fundamental determinant of cardiovascular homeostasis. …

Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?

D Fulton, JP Gratton, WC Sessa - Journal of Pharmacology and …, 2001 - ASPET
Endothelial nitric oxide synthase (eNOS) is important for cardiovascular homeostasis, vessel
remodeling, and angiogenesis. Given the impact of endothelium- derived nitric oxide (NO) …

[HTML][HTML] Enhanced electron flux and reduced calmodulin dissociation may explain “calcium-independent” eNOS activation by phosphorylation

TJ McCabe, D Fulton, LJ Roman, WC Sessa - Journal of Biological …, 2000 - ASBMB
Bovine endothelial nitric oxide synthase (eNOS) is phosphorylated directly by the protein
kinase Akt at serine 1179. Mutation of this residue to the negatively charged aspartate (S1179D …