Structure–activity studies with ring E analogues of methyllycaconitine on bovine adrenal α3β4* nicotinic receptors

DL Bryant, RB Free, SM Thomasy, DJ Lapinsky… - Neuroscience …, 2002 - Elsevier
The development of new agents that selectively interact with subtypes of neuronal nicotinic
receptors (nAChRs) is of primary importance for the study of physiological processes and …

Structure activity studies of ring E analogues of methyllycaconitine. Part 2: Synthesis of antagonists to the α3β4* nicotinic acetylcholine receptors through modifications …

…, KA Ismail, KM Arason, S McKay, DL Bryant… - Bioorganic & medicinal …, 2004 - Elsevier
The development of novel agents for the differentiation of neuronal nicotinic acetylcholine
receptors (nAChRs) is important for the treatment of a variety of pathological conditions. We …

Evidence for spare nicotinic acetylcholine receptors and a β4 subunit in bovine adrenal chromaffin cells: studies using bromoacetylcholine, epibatidine, cytisine and …

BW Wenger, DL Bryant, RT Boyd, DB McKay - Journal of Pharmacology and …, 1997 - ASPET
Relatively little is known about the type and number of nicotinic acetylcholine receptors (nAChRs)
that mediate secretion from adrenal chromaffin cells. In these studies, we investigated …

Analogs of methyllycaconitine as novel noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and …

…, SB McKay, RA El-Hajj, DL Bryant… - Molecular …, 2007 - ASPET
As a novel approach to drug discovery involving neuronal nicotinic acetylcholine receptors (nAChRs),
our laboratory targeted nonagonist binding sites (ie, noncompetitive binding sites, …

[3H] Epibatidine binding to bovine adrenal medulla: evidence for α3β4* nicotinic receptors

RB Free, DL Bryant, SB McKay, DJ Kaser… - Neuroscience letters, 2002 - Elsevier
In these studies, [ 3 H]epibatidine is used as the radioligand to characterize nicotinic
acetylcholine receptors (nAChRs) from bovine adrenal medulla. Specific binding reaches …

Effects of methyllycaconitine and related analogues on bovine adrenal α3β4* nicotinic acetylcholine receptors

DL Bryant, RB Free, SM Thomasy… - Annals of the New …, 2002 - Wiley Online Library
Adrenal secretion and binding studies were performed using ring E analogues of methyllycaconitine
to assess structural determinants affecting activity on bovine adrenal α3β4* nicotinic …

Breast cancer in the personal genomics era

RE Ellsworth, DJ Decewicz, CD Shriver… - Current …, 2010 - ingentaconnect.com
Breast cancer is a heterogeneous disease with a complex etiology that develops from different
cellular lineages, progresses along multiple molecular pathways, and demonstrates wide …

[BOOK][B] An examination of prayer in the Johannine literature

ML Bryant - 2008 - search.proquest.com
This dissertation is an examination of every prayer reference in the relevant Johannine
literature, the Fourth Gospel, 1 John, and Revelation. The aim of the study is to provide a …

[HTML][HTML] Integrated amplification microarrays for infectious disease diagnostics

DP Chandler, L Bryant, SB Griesemer, R Gu… - Microarrays, 2012 - mdpi.com
This overview describes microarray-based tests that combine solution-phase amplification
chemistry and microarray hybridization within a single microfluidic chamber. The integrated …

Sacrificing the sacrifice of animals: legal personhood for animals, the status of animals as property, and the presumed primacy of humans

TL Bryant - Rutgers LJ, 2007 - HeinOnline
… with another chimpanzee named Darrell.Kermit and Darrell were supposed to be housed
together at PPI.Like all the other OSU chimpanzees and monkeys, Darrell had been trained in …