A simplified method for assessing drug effects on gastric emptying in rats

DA Droppleman, RL Gregory, RS Alphin - Journal of pharmacological …, 1980 - Elsevier
A method is described to determine the effects of experimental compounds on gastric emptying
in rats. The technique, using a methylcellulose-based test meal, is simple, versatile and …

Interactions of adenosine A1 receptor-mediated renal vasoconstriction with endogenous nitric oxide and ANG II

RJ Barrett, DA Droppleman - American Journal of …, 1993 - journals.physiology.org
Renal vasoconstrictor responses to the adenosine A1 agonist N6-cyclopentyladenosine (CPA)
were compared in the in situ autoperfused rat kidney to responses evoked by angiotensin …

Apparent microwave emissivity of sea foam

JD Droppleman - Journal of Geophysical Research, 1970 - Wiley Online Library
… emissivity with the ratio of the thickness d of the foam to the wavelength k for the frequencies
34, 19, 10, and 1.4 GHz. The broad band is an envelope containing the values of the …

An airborne measurement of the salinity variations of the Mississippi River outflow

JD Droppleman, RA Mennella… - Journal of Geophysical …, 1970 - Wiley Online Library
… The salinity magnitudes interpreted from the observed changes in radiometric temperature
at 1.420 GHz as a function of d•stance from the mouth of the southwest pass. Uncertainties in …

N-0861 selectively antagonizes adenosine A1 receptors in vivo

RJ Barrett, DA Droppleman, KF Wright - European journal of pharmacology, 1992 - Elsevier
Experiments were performed to determine the antagonistic actions of (±)N 6 -endonorbornan-2-yl-9-methyladenine
(N-0861) at A 1 and A 2 adenosine receptors in vivo, and to evaluate …

New method for evaluating topical action of substances on gastric mucosa

RS Alphin, DA Droppleman - Journal of Pharmaceutical Sciences, 1971 - Elsevier
… simultaneously on adjacent mucosal areas; (b) the quantity of material applied and exposure
time may be easily varied; (c) gastrotoxic effects can be observed as they occur; and (d) the …

Discrimination of A1 versus A2 receptor subtype selectivity of adenosine receptor agonists in vivo.

RJ Barrett, DA Droppleman, KF Wright - Journal of Pharmacology and …, 1994 - ASPET
Previous attempts to discern and quantify the selectivity of agonists for A1 versus A2 adenosine
receptors in vivo have been confounded by the activation of baroreceptor reflexes and/or …

Pharmacology and toxicology of the A2A‐adenosine receptor agonist 2‐ [(cyclohexylmethylene)hydrazino]adenosine (MRE‐0470) in the rat

…, DA Droppleman, KF Wright, D Mossem - Drug development …, 1997 - Wiley Online Library
2‐[(cyclohexylmethylene)hydrazino]adenosine (MRE‐0470) is an A 2A ‐adenosine receptor
agonist that is a potent and selective coronary vasodilator. As part of a preclinical program, …

AHR-9294: a novel inhibitor of H, K-ATPase antagonizes gastric HCl secretion in vivo.

…, LM Pinkus, J Bailey, WL Smith, D Droppleman… - … of Pharmacology and …, 1992 - ASPET
8-Methoxy-4-[(2-isopropylphenyl)amino]-3-quinolinecarboxylate ethyl ester (AHR-9294)
inhibited acid secretion stimulated by histamine, pentagastrin or carbachol in rats, and by …

Salinity surveys using an airborne microwave radiometer

JF Paris, JD Droppleman, DE Evans - … Program Rev., Vol. 1 27p (SEE …, 1972 - ntrs.nasa.gov
The Barnes PRT-5 infrared radiometer and L-band channel of the multifrequency microwave
radiometer are used to survey the distribution of surface water temperature and salinity. …