When the Endogenous Hallucinogenic Trace Amine N,N-Dimethyltryptamine Meets the Sigma-1 Receptor
TP Su, T Hayashi, DB Vaupel - Science signaling, 2009 - science.org
N,N-dimethyltryptamine (DMT) is a hallucinogen found endogenously in human brain that is
commonly recognized to target the 5-hydroxytryptamine 2A receptor or the trace amine–…
commonly recognized to target the 5-hydroxytryptamine 2A receptor or the trace amine–…
Naltrexone fails to antagonize the σ effects of PCP and SKF 10,047 in the dog
DB Vaupel - European journal of pharmacology, 1983 - Elsevier
… DB VAUPEL, Naltrexone fails to antagonize the o effects of PCP and SKF 10.047 in the dog,
… Vaupel, DB, 1982, Lack of pharmacologic specificity and selectivity between the d (+) and 1 (…
… Vaupel, DB, 1982, Lack of pharmacologic specificity and selectivity between the d (+) and 1 (…
Nitric oxide synthase inhibitors
DB Vaupel, AS Kimes, ED London - Neuropsychopharmacology, 1995 - nature.com
Four inhibitors of nitric oxide synthase (NOS), administered as acute pretreatments, attenuated
several signs of naloxone-precipitated opioid withdrawal in morphine-dependent rats. …
several signs of naloxone-precipitated opioid withdrawal in morphine-dependent rats. …
Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380
…, CS Contoreggi, AG Horti, DB Vaupel… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Assays of human postmortem brain tissue have revealed that smokers have greater densities
of high-affinity nicotinic acetylcholine receptors (nAChRs) in several brain regions than do …
of high-affinity nicotinic acetylcholine receptors (nAChRs) in several brain regions than do …
5-Iodo-A-85380, an α4β2 subtype-selective ligand for nicotinic acetylcholine receptors
…, G Tamagnan, AS Kimes, J Chambers, DB Vaupel… - Molecular …, 2000 - ASPET
In an effort to develop selective radioligands for in vivo imaging of neuronal nicotinic
acetylcholine receptors (nAChRs), we synthesized 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine (5-…
acetylcholine receptors (nAChRs), we synthesized 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine (5-…
Attenuation of some signs of opioid withdrawal by inhibitors of nitric oxide synthase
AS Kimes, DB Vaupel, ED London - Psychopharmacology, 1993 - Springer
Abstract Effects of nitric oxide synthase (NOS) inhibitors (l-N G -nitroarginine,l-N G -nitroarginine
methyl ester) on precipitated opioid withdrawal were studied in morphine-dependent …
methyl ester) on precipitated opioid withdrawal were studied in morphine-dependent …
Quantification of nicotinic acetylcholine receptors in the human brain with PET: bolus plus infusion administration of 2-[18F] F-A85380
…, SI Chefer, JA Matochik, CS Contoreggi, DB Vaupel… - Neuroimage, 2008 - Elsevier
Quantitative analysis of most positron emission tomography (PET) data requires arterial blood
sampling and dynamic scanning when the radioligand is administered as a bolus injection…
sampling and dynamic scanning when the radioligand is administered as a bolus injection…
Abstinence from cocaine and sucrose self-administration reveals altered mesocorticolimbic circuit connectivity by resting state MRI
Previous preclinical studies have emphasized that drugs of abuse, through actions within
and between mesocorticolimbic (MCL) regions, usurp learning and memory processes …
and between mesocorticolimbic (MCL) regions, usurp learning and memory processes …
Further in vivo studies on attenuating morphine withdrawal: isoform-selective nitric oxide synthase inhibitors differ in efficacy
DB Vaupel, AS Kimes, ED London - European journal of pharmacology, 1997 - Elsevier
The N-methyl-d-aspartate (NMDA) receptor–nitric oxide (NO) pathway has been linked to
opiate withdrawal. Pretreatments with four inhibitors of NO synthase, 7-nitro indazole, 3-bromo-…
opiate withdrawal. Pretreatments with four inhibitors of NO synthase, 7-nitro indazole, 3-bromo-…
[HTML][HTML] Inhibitors of nitric oxide synthase and the opioid withdrawal syndrome
ED London, AS Kimes, DB Vaupel - NIDA research monograph, 1995 - books.google.com
Nitric oxide (NO) is a free radical gas that is purported to have a neurotransmitter function (Garthwaite
1991; Garthwaite et al. 1988). The production of NO has been linked to activity of …
1991; Garthwaite et al. 1988). The production of NO has been linked to activity of …