The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF)
PF Smith, K Maclennan, CL Darlington - Journal of ethnopharmacology, 1996 - Elsevier
Ginkgo biloba (Ginkgoaceae) is an ancient Chinese tree which has been cultivated and held
sacred for its health-promoting properties. There is substantial experimental evidence to …
sacred for its health-promoting properties. There is substantial experimental evidence to …
The CNS effects of Ginkgo biloba extracts and ginkgolide B
KM Maclennan, CL Darlington, PF Smith - Progress in neurobiology, 2002 - Elsevier
Ginkgo biloba extracts such as EGb-761 have been suggested to have a multitude of
beneficial effects on CNS function, from enhancing cognitive function in dementia to facilitating …
beneficial effects on CNS function, from enhancing cognitive function in dementia to facilitating …
Expression of the cannabinoid CB2 receptor in the rat cerebellum: an immunohistochemical study
JC Ashton, D Friberg, CL Darlington, PF Smith - Neuroscience letters, 2006 - Elsevier
Reports of cannabinoid CB2 receptor protein in the brain have been ambiguous. We therefore
tested for CB2 immunoreactivity in the rat brain using immunofluorescence. We detected …
tested for CB2 immunoreactivity in the rat brain using immunofluorescence. We detected …
Long-term effects of permanent vestibular lesions on hippocampal spatial firing
…, A Horii, PF Smith, CL Darlington… - Journal of …, 2003 - Soc Neuroscience
The hippocampus is thought to be important for spatial representation processes that depend
on the integration of both self-movement and allocentric cues. The vestibular system is a …
on the integration of both self-movement and allocentric cues. The vestibular system is a …
Does vestibular damage cause cognitive dysfunction in humans?
…, Y Zheng, A Horii, CL Darlington - Journal of Vestibular …, 2005 - content.iospress.com
For more than a decade, evidence from animal studies has suggested that damage to the
vestibular system leads to deficits in spatial navigation which are indicative of impaired spatial …
vestibular system leads to deficits in spatial navigation which are indicative of impaired spatial …
Molecular mechanisms of recovery from vestibular damage in mammals: recent advances
CL Darlington, PF Smith - Progress in neurobiology, 2000 - Elsevier
The aim of this review is to summarise and critically evaluate studies of vestibular compensation
published over the last 2 years, with emphasis on those concerned with the molecular …
published over the last 2 years, with emphasis on those concerned with the molecular …
Lesions of the vestibular system disrupt hippocampal theta rhythm in the rat
…, A Horii, PF Smith, CL Darlington… - Journal of …, 2006 - journals.physiology.org
The hippocampus has a major role in memory for spatial location. Theta is a rhythmic
hippocampal EEG oscillation that occurs at ∼8 Hz during voluntary movement and that may have …
hippocampal EEG oscillation that occurs at ∼8 Hz during voluntary movement and that may have …
Move it or lose it—is stimulation of the vestibular system necessary for normal spatial memory?
PF Smith, CL Darlington, Y Zheng - Hippocampus, 2010 - Wiley Online Library
Studies in both experimental animals and human patients have demonstrated that
peripheral vestibular lesions, especially bilateral lesions, are associated with spatial memory …
peripheral vestibular lesions, especially bilateral lesions, are associated with spatial memory …
Evidence that spatial memory deficits following bilateral vestibular deafferentation in rats are probably permanent
JH Baek, Y Zheng, CL Darlington, PF Smith - Neurobiology of Learning and …, 2010 - Elsevier
Previous studies of rats with bilateral vestibular deafferentation (BVD) have demonstrated
spatial memory deficits, suggesting adverse effects on the hippocampus. However, the longest …
spatial memory deficits, suggesting adverse effects on the hippocampus. However, the longest …
The contribution of the intrinsic excitability of vestibular nucleus neurons to recovery from vestibular damage
CL Darlington, MB Dutia… - European Journal of …, 2002 - Wiley Online Library
Damage to the peripheral vestibular system results in a syndrome of ocular motor and
postural abnormalities that partially and gradually abate over time in a process known as ‘…
postural abnormalities that partially and gradually abate over time in a process known as ‘…