User profiles for Craig R. Rush

Craig R. Rush

Professor, University of Kentucky
Verified email at email.uky.edu
Cited by 7995

Impaired inhibitory control of behavior in chronic cocaine users

MT Fillmore, CR Rush - Drug and alcohol dependence, 2002 - Elsevier
This study examined the ability to inhibit and execute behavioral responses in adult cocaine
users and in an aged-matched sample with no history of cocaine use. Subjects (n=22) were …

Assessing the abuse potential of methylphenidate in nonhuman and human subjects: a review

SH Kollins, EK MacDonald, CR Rush - Pharmacology Biochemistry and …, 2001 - Elsevier
Methylphenidate (MPH) is widely used for the treatment of Attention Deficit Hyperactivity
Disorder (ADHD) in children, adolescents, and adults. Methylphenidate is clearly effective for …

Acute effects of cocaine in two models of inhibitory control: implications of non‐linear dose effects

MT Fillmore, CR Rush, L Hays - Addiction, 2006 - Wiley Online Library
Aims This study examined dose–response effects of oral cocaine on the inhibitory control of
behavior in adult cocaine users using two different behavioral models of inhibitory control. …

Individual differences in drug abuse vulnerability: d-amphetamine and sensation-seeking status

…, MT Fillmore, SD Lane, NG Harrington, CR Rush - …, 2006 - Springer
Rationale While the personality dimensions of novelty seeking and sensation seeking are
associated with drug abuse vulnerability, the mechanisms associated with this vulnerability …

Evaluation of the “pipeline” for development of medications for cocaine use disorder: a review of translational preclinical, human laboratory, and clinical trial research

PW Czoty, WW Stoops, CR Rush - Pharmacological reviews, 2016 - ASPET
Cocaine use disorder is a persistent public health problem for which no widely effective
medications exist. Self-administration procedures, which have shown good predictive validity in …

Acute effects of oral cocaine on inhibitory control of behavior in humans

MT Fillmore, CR Rush, L Hays - Drug and alcohol dependence, 2002 - Elsevier
Studies of humans show that individuals with histories of cocaine abuse display reduced
inhibitory control over behavioral impulses. The present study tested the effects of oral cocaine …

Polydrug abusers display impaired discrimination-reversal learning in a model of behavioural control

MT Fillmore, CR Rush - Journal of psychopharmacology, 2006 - journals.sagepub.com
Long-term cocaine and alcohol use is associated with neuropsychological impairments that
implicate poor inhibitory mechanisms of behavioural control. This study tested acquisition …

Validation of the multiple-choice procedure for investigating drug reinforcement in humans.

RR Griffiths, CR Rush, KA Puhala - Experimental and Clinical …, 1996 - psycnet.apa.org
Three experiments demonstrated the validity of studying drug reinforcement in humans by
using a novel Multiple-Choice Procedure. The distinguishing characteristic of the procedure is …

Reinforcing and subject-rated effects of methylphenidate and d-amphetamine in non–drug-abusing humans

CR Rush, WD Essman, CA Simpson… - Journal of clinical …, 2001 - journals.lww.com
The reinforcing effects of methylphenidate (20–40 mg), d-amphetamine (10–20 mg), and
placebo were assessed in eight healthy, non–sleep-deprived, non–drug-abusing outpatient …

An update on the clinical pharmacology of methylphenidate: therapeutic efficacy, abuse potential and future considerations

…, WW Stoops, JA Lile, CR Rush - Expert Review of …, 2020 - Taylor & Francis
Introduction Methylphenidate remains a first-line medication for treating ADHD in children
and adults. However, its behavioral pharmacological similarities to methamphetamine and …