[HTML][HTML] Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of …
…, A Coste, C Lanneau, C Desvignes… - …, 2005 - nature.com
Noncompetitive N-methyl-D-aspartate (NMDA) blockers induce schizophrenic-like symptoms
in humans, presumably by impairing glutamatergic transmission. Therefore, a compound …
in humans, presumably by impairing glutamatergic transmission. Therefore, a compound …
Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia
…, A Coste, C Lanneau, C Desvignes… - Pharmacology …, 2008 - Elsevier
On native human, rat and mouse glycine transporter-1(GlyT1), SSR130800 behaves as a
selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked …
selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked …
First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities
…, AJ Aubin, A Tarafder, M Cazes, C Desvignes… - … of pharmaceutical and …, 2018 - Elsevier
Supercritical Fluid Chromatography (SFC) has known a strong regain of interest for the last
10 years, especially in the field of pharmaceutical analysis. Besides the development and …
10 years, especially in the field of pharmaceutical analysis. Besides the development and …
Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function
…, M Poncelet, C Gueudet, C Desvignes… - … of Pharmacology and …, 2001 - ASPET
The present study investigated the effects of the selective neurokinin-2 (NK 2 ) receptor
antagonist SR48968 in behavioral, electrophysiological, and biochemical tests sensitive to the …
antagonist SR48968 in behavioral, electrophysiological, and biochemical tests sensitive to the …
[HTML][HTML] The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with …
…, R Featherstone, S Sahni, H Defex, C Desvignes… - Scientific reports, 2016 - nature.com
Normalization of altered glutamate neurotransmission through activation of the mGluR2 has
emerged as a new approach to treat schizophrenia. These studies describe a potent brain …
emerged as a new approach to treat schizophrenia. These studies describe a potent brain …
Evidence that the neuronal nitric oxide synthase inhibitor 7-nitroindazole inhibits monoamine oxidase in the rat: in vivo effects on extracellular striatal dopamine and 3 …
The present study investigated in vivo the kinetics of the changes in rat striatal extracellular
concentrations of dopamine (DA), and its monoamine oxidase (MAO)-derived metabolite 3,4-…
concentrations of dopamine (DA), and its monoamine oxidase (MAO)-derived metabolite 3,4-…
Protein mapping of peanut extract with capillary electrophoresis
L Villemet, A Cuchet, C Desvignes… - …, 2022 - Wiley Online Library
Protein separation can be achieved with different modes of capillary electrophoresis, such
as with capillary gel electroporesis (CGE) or with capillary zone electrophoresis (CZE). CZE …
as with capillary gel electroporesis (CGE) or with capillary zone electrophoresis (CZE). CZE …
Monitoring nitric oxide (NO) in rat locus coeruleus: differential effects of NO synthase inhibitors
C Desvignes, F Robert, C Vachette, G Chouvet… - …, 1997 - journals.lww.com
A porphyrinic microsensor combined with in vivo voltammetry was used to monitor extracellular
nitric oxide (NO) in the locus coeruleus (LC) of anaesthetized rats. Administration of N ω-…
nitric oxide (NO) in the locus coeruleus (LC) of anaesthetized rats. Administration of N ω-…
SSR240600 [(R)-2-(1-{2-[4-{2-[3, 5-Bis (trifluoromethyl) phenyl] acetyl}-2-(3, 4-dichlorophenyl)-2-morpholinyl] ethyl}-4-piperidinyl)-2-methylpropanamide], a Centrally …
R Steinberg, R Alonso, L Rouquier, C Desvignes… - … of Pharmacology and …, 2002 - ASPET
… Régis Steinberg, Richard Alonso, Liliane Rouquier, Christophe Desvignes, Jean-Claude
Michaud, Annie Cudennec, Mireille Jung, Jacques Simiand, Guy Griebel, Xavier Emonds-Alt, …
Michaud, Annie Cudennec, Mireille Jung, Jacques Simiand, Guy Griebel, Xavier Emonds-Alt, …
[PDF][PDF] Reliances tectoniques enjeux constructifs d9une architecture des milieux
C Desvignes - academia.edu
En tant que de directeur de recherches pour ce mémoire, Stéphane Bonzani mAa offert les
meilleures conditions pour sa réalisation. JAai apprécié la générosité avec la= quelle il a …
meilleures conditions pour sa réalisation. JAai apprécié la générosité avec la= quelle il a …