User profiles for Christine M. Gall
Christine M Gall, Professor and ChairDepartment of Anatomy and Neurobiology, UCI Verified email at uci.edu Cited by 29237 |
Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport
JM Conner, JC Lauterborn, Q Yan, CM Gall… - Journal of …, 1997 - Soc Neuroscience
A sensitive immunohistochemical technique was used, along with highly specific affinity-purified
antibodies to brain-derived neurotrophic factor (BDNF), to generate a detailed mapping …
antibodies to brain-derived neurotrophic factor (BDNF), to generate a detailed mapping …
BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF
PJ Isackson, MM Huntsman, KD Murray, CM Gall - Neuron, 1991 - cell.com
We have localized brain-derived neurotrophic factor (BDNF) mRNA in rat brain and examined
its regulation by seizure activity. In situ hybridization of BDNF 35S-cRNA most prominently …
its regulation by seizure activity. In situ hybridization of BDNF 35S-cRNA most prominently …
At the interface of sensory and motor dysfunctions and Alzheimer's disease
…, DP Devanand, CJ Duffy, CM Gall… - Alzheimer's & …, 2015 - Elsevier
Recent evidence indicates that sensory and motor changes may precede the cognitive
symptoms of Alzheimer's disease (AD) by several years and may signify increased risk of …
symptoms of Alzheimer's disease (AD) by several years and may signify increased risk of …
BDNF and epilepsy: too much of a good thing?
76 Bradbury, EJ et al.(2000) Chrondroitinase ABC delivered to the site of a spinal cord injury
upregulates GAP-43 expression in dorsal root ganglion neurons. Soc. Neurosci. Abstr. 26, p…
upregulates GAP-43 expression in dorsal root ganglion neurons. Soc. Neurosci. Abstr. 26, p…
Limbic seizures increase neuronal production of messenger RNA for nerve growth factor
CM Gall, PJ Isackson - Science, 1989 - science.org
Nerve growth factor (NGF) produced by telencephalic neurons provides critical trophic
support for cholinergic neurons of the basal forebrain. In situ hybridization and nuclease …
support for cholinergic neurons of the basal forebrain. In situ hybridization and nuclease …
Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors
…, PM Maras, DE Grigoriadis, CM Gall… - Journal of …, 2010 - Soc Neuroscience
Chronic stress impairs learning and memory in humans and rodents and disrupts long-term
potentiation (LTP) in animal models. These effects are associated with structural changes in …
potentiation (LTP) in animal models. These effects are associated with structural changes in …
Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus
Brain-derived neurotrophic factor (BDNF) is an extremely potent, positive modulator of theta
burst induced long-term potentiation (LTP) in the adult hippocampus. The present studies …
burst induced long-term potentiation (LTP) in the adult hippocampus. The present studies …
Changes in synaptic morphology accompany actin signaling during LTP
Stabilization of long-term potentiation (LTP) is commonly proposed to involve changes in
synaptic morphology and reorganization of the spine cytoskeleton. Here we tested whether, as …
synaptic morphology and reorganization of the spine cytoskeleton. Here we tested whether, as …
Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons
…, G Lynch, P Vanderklish, A Arai, CM Gall - Journal of …, 2000 - Soc Neuroscience
This study investigated whether positive modulators of AMPA-type glutamate receptors
influence neurotrophin expression by forebrain neurons. Treatments with the ampakine CX614 …
influence neurotrophin expression by forebrain neurons. Treatments with the ampakine CX614 …
Dopaminergic neurons in rat ventral midbrain express brain‐derived neurotrophic factor and neurotrophin‐3 mRNAs
…, KM Guthrie, PJ Isackson, CM Gall - Journal of …, 1994 - Wiley Online Library
Studies of the trophic activities of brain‐derived neurotrophic factor and neurotrophin‐3 indicate
that both molecules support the survival of a number of different embryonic cell types in …
that both molecules support the survival of a number of different embryonic cell types in …