The mother or the fetus? 11β-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous …
MC Holmes, CT Abrahamsen, KL French… - Journal of …, 2006 - Soc Neuroscience
Low birth weight associates with increased susceptibility to adult cardiometabolic and
affective disorders spawning the notion of fetal “programming.” Prenatal exposure to excess …
affective disorders spawning the notion of fetal “programming.” Prenatal exposure to excess …
Effects of angiotensins II and IV on blood pressure, renal function, and PAI-1 expression in the heart and kidney of the rat
CT Abrahamsen, MA Pullen, CG Schnackenberg… - Pharmacology, 2002 - karger.com
The role of angiotensin II (AII) and angiotensin IV (AIV) as inducers of PAI-1 expression during
hypertension was studied in vivo. A 2-week infusion of AII (300 ng/kg/min) via an osmotic …
hypertension was studied in vivo. A 2-week infusion of AII (300 ng/kg/min) via an osmotic …
The angiotensin type 1 receptor antagonist, eprosartan, attenuates the progression of renal disease in spontaneously hypertensive stroke-prone rats with accelerated …
CT Abrahamsen, FC Barone, WG Campbell… - … of Pharmacology and …, 2002 - ASPET
The effects of the angiotensin type 1 (AT 1 ) receptor antagonist, eprosartan, were studied in
a model of severe, chronic hypertension. Treatment of male spontaneously hypertensive …
a model of severe, chronic hypertension. Treatment of male spontaneously hypertensive …
Primary immunodeficiency diseases: genomic approaches delineate heterogeneous Mendelian disorders
…, SF Jørgensen, TG Abrahamsen, T Øverland… - Journal of Allergy and …, 2017 - Elsevier
Background Primary immunodeficiency diseases (PIDDs) are clinically and genetically
heterogeneous disorders thus far associated with mutations in more than 300 genes. The clinical …
heterogeneous disorders thus far associated with mutations in more than 300 genes. The clinical …
[PDF][PDF] PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia
…, G Nishimura, CF Rustad, TG Abrahamsen… - The American Journal of …, 2014 - cell.com
Human phosphoglucomutase 3 (PGM3) catalyzes the conversion of N-acetyl-glucosamine (GlcNAc)-6-phosphate
into GlcNAc-1-phosphate during the synthesis of uridine diphosphate (…
into GlcNAc-1-phosphate during the synthesis of uridine diphosphate (…
[HTML][HTML] TTC7A mutations disrupt intestinal epithelial apicobasal polarity
…, P Schlesser, TG Abrahamsen… - The Journal of …, 2014 - Am Soc Clin Investig
Multiple intestinal atresia (MIA) is a rare cause of bowel obstruction that is sometimes
associated with a combined immunodeficiency (CID), leading to increased susceptibility to …
associated with a combined immunodeficiency (CID), leading to increased susceptibility to …
Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) …
…, T Seierstad, M Johansen, TW Abrahamsen… - The lancet …, 2010 - thelancet.com
Background Histone deacetylase (HDAC) inhibitors have shown radiosensitising activity in
preclinical tumour models. This phase 1 study assessed the use of vorinostat combined with …
preclinical tumour models. This phase 1 study assessed the use of vorinostat combined with …
Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature
…, D Fadnes, TG Abrahamsen… - Proceedings of the …, 2009 - National Acad Sciences
Complement component C5 is crucial for experimental animal inflammatory tissue damage;
however, its involvement in human inflammation is incompletely understood. The responses …
however, its involvement in human inflammation is incompletely understood. The responses …
[HTML][HTML] Second-tier next generation sequencing integrated in nationwide newborn screening provides rapid molecular diagnostics of severe combined …
…, J Buechner, T Øverland, TG Abrahamsen… - Frontiers in …, 2020 - frontiersin.org
Severe combined immunodeficiency (SCID) and other T cell lymphopenias can be detected
during newborn screening (NBS) by measuring T cell receptor excision circles (TRECs) in …
during newborn screening (NBS) by measuring T cell receptor excision circles (TRECs) in …
Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study
Background Lymphoproliferation and autoimmune cytopenias characterise autoimmune
lymphoproliferative syndrome. Other conditions sharing these manifestations have been termed …
lymphoproliferative syndrome. Other conditions sharing these manifestations have been termed …