There are few reports describing the role of p53-dependent gene repression in apoptotic
cell death. To identify such apoptosis-associated p53 target genes, we used the pro-oxidant …

Methyltransferase inhibitors commonly used in clinical trials promote tumor cell death, but
their detailed cytotoxic action is not yet fully understood. A deeper knowledge about their …

Intestinal hexose absorption and gluconeogenesis have been studied in relation to refeeding
after two different fasting phases: a long period of protein sparing during which energy …

Intestinal villus atrophy through prolonged fasting was studied according to two different
metabolic phases reached by fasting animals and characterized by (a) the mobilization of fat …

The intestine is characterized by morphofunctional differences along the proximodistal axis.
The aim of this study was to derive mesenchymal cell lines representative of the gut axis. We …

The regulatory effect of epidermal growth factor (EGF) on the postnatal maturation of sucrase
was investigated in the small intestine of suckling and weanling rats. Administration of EGF (…

The expression of lactase was compared in the jejunum and colon of the rat at the levels of
enzyme activity and protein and RNA content. We found that the enzyme proteins and the …

Intestinal apoptosis and expression of apoptosis inducers – the cytokines TNFα, TGFβ1 –
and the intestinal transcription factor Cdx2, were studied according to two different metabolic …

The evolution pattern of brush-border digestive hydrolases and their hormonal regulation
were studied in the proximal colon of newborn rats. The potentiality of the colon to express a …

The effect of starvation and refeeding on the developmental pattern of intestinal sucrase-isomaltase
(SI) was analyzed in preweaned rats. Starvation at postnatal day 12 caused a …