The mechanism of protamine-induced hypotension and bradycardia was investigated in
anesthetized, heparinized dogs. Several groups of animals with intact circulation were studied …

The mechanisms underlying protamine-induced hypotension and bradycardia were the
subject of this investigation. Six groups of dogs with intact circulation were tested in controlled …

In dogs, the oral administration of prednisolone phosphate at 50 mg/day for 14 days did not
induce significant adrenocortical suppression as evidenced by a pronounced elevation in …

It was not possible to induce hyperglycemia in dogs and rabbits with nontoxic doses of
histamine injected intravenously, whereas a moderate hyperglycemia occurred in both species …

This investigation was designed to reevaluate the presently accepted mechanism of "nicotine
reversal" in dogs subjected to alpha adrenergic blockade. For this reason, the induction of …

We have attempted to establish the mechanism of a prolonged pressor response to nicotine
in anesthetized, atropinized dogs treated with the a-adrenergic blocker, phenoxybenzamine. …

In dogs, the administration of dexamethasone induced adrenocortical suppression as
evidenced, 72 hours after withdrawal of steroid, by failure of a normal elevation in plasma …

In anesthetized rabbits, lethal doses of compound 48/80 produced marked depression of
respiration with ensuing blood pressure changes that could be altered by administering …

Five new 3-aminoalkoxy derivatives of quinuclidine have been synthesized. All compounds
reduced blood pressure in dogs to varying degrees, the most effective being 3-(3-…

o 1. In anesthetized, atropinized dogs which have received a high dose of the alpha adrenergic
blocking agent, phenoxybenzamine, nicotine salicylate 0.2 mg/kg iv induces a blood …