… ZEEB, MD, CARL C. S1m, PhD.,t and JC WEETE, M)D. … C., and Zeek, PM Studies on
periarteritis nodosa. II. The role of various factors in theetiology of periarteritis nodosa in …

Indications of possible health effects of residue organics in drinking water have been sought
using short‐term tests of mutagenic and transforming activity. Ten percent or less of the total …

The effect of supplemental ascorbic acid and α-tocopherol on fecal mutagenicity was examined
in 2 studies involving 20 healthy human donors aged 22–55 years. The vitamins were …

A polychlorinated biphenyl mixture, Aroclor 1254, two commercial grade insecticides, mirex
and kepone, and a pesticide breakdown product, 1,2,4-trichlorobenzene were evaluated for …

The author's aim has been to devise a reliable test giving the maximum information on the
toxicity of a drug with minimal expenditure of time and material during the screening of a …

REsULTS The lesions were similar in rats and dogs and consisted of varying degrees of
fibrinoid necrosis and inflammatory exudate in the walls of smal and medium-sized arteries, …

It is known that Chlorguanide (CG) [Proguanil] is converted in vivo to at least two metabolites
which have been isolated in crystalline form from monkey urine. One of these, a triazine (…

Methods The rats used were albinos of both sexes, of the Wistar and Sprague-Dawley strains.
The animals were about 6 months of age when oper-ated upon and were fed only Purina …

By using chromodacryorrhea, the phenomenon of the shedding of bloody tears by rats, as a
criterion, acetylcholine can be detected in as small amount as 0.2 γ. 2. Since there are 4 …

Many studies have been performed on the in vivo teratogenicity of cyclophosphamide, and
there is uncertainty whether the parent compound or P‐450 generated alkylating metabolite(s…