[HTML][HTML] Identification of Key Residues for Interaction of Vasoactive Intestinal Peptide with Human VPAC1 and VPAC2Receptors and Development of a Highly …
P Nicole, L Lins, C Rouyer-Fessard, C Drouot… - Journal of Biological …, 2000 - ASBMB
The widespread neuropeptide vasoactive intestinal peptide (VIP) has two receptors VPAC 1
and VPAC 2 . Solid-phase syntheses of VIP analogs in which each amino acid has been …
and VPAC 2 . Solid-phase syntheses of VIP analogs in which each amino acid has been …
[HTML][HTML] Orexins acting at native OX1 receptor in colon cancer and neuroblastoma cells or at recombinant OX1 receptor suppress cell growth by inducing apoptosis
P Rouet-Benzineb, C Rouyer-Fessard, A Jarry… - Journal of Biological …, 2004 - ASBMB
Screening of 26 gut peptides for their ability to inhibit growth of human colon cancer HT29-D4
cells grown in 10% fetal calf serum identified orexin-A and orexin-B as anti-growth factors. …
cells grown in 10% fetal calf serum identified orexin-A and orexin-B as anti-growth factors. …
Neurotensin and a non‐peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice
JJ Maoret, Y Anini, C Rouyer‐Fessard… - … journal of cancer, 1999 - Wiley Online Library
The intestine is a large endocrine organ, but the dependence of colon cancer on hormones
remains unknown. We show here that neurotensin, a paracrine/endocrine peptide in the gut, …
remains unknown. We show here that neurotensin, a paracrine/endocrine peptide in the gut, …
Enterocytic differentiation and glucose utilization in the human colon tumor cell line Caco‐2: Modulation by forskolin
…, G Chevalier, C Rouyer‐Fessard… - Journal of cellular …, 1985 - Wiley Online Library
The human colon cancer line Caco‐2 exhibits after confluency a concomitant increase of
glycogen accumulation and an enterocytic differentiation. The purpose of this work was to …
glycogen accumulation and an enterocytic differentiation. The purpose of this work was to …
Receptors for insulin-like growth factors I and II in rat gastrointestinal epithelium
M Laburthe, C Rouyer-Fessard… - American Journal of …, 1988 - journals.physiology.org
Distinct receptors for insulin-like growth factors (IGFs) have been characterized in rat intestinal
epithelium using 125I-labeled IGF-I and 125I-labeled IGF-II. In jejunal epithelial plasma …
epithelium using 125I-labeled IGF-I and 125I-labeled IGF-II. In jejunal epithelial plasma …
Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis
T Voisin, A El Firar, M Fasseu, C Rouyer-Fessard… - Cancer research, 2011 - AACR
Resistance to apoptosis is a recurrent theme in colon cancer. We have shown previously
that the 7-transmembrane spanning receptor OX1R for orexins promotes robust apoptosis in …
that the 7-transmembrane spanning receptor OX1R for orexins promotes robust apoptosis in …
Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: structure-function relationship with …
…, JJ Maoret, C Rouyer-Fessard… - Annals of the New …, 1996 - pubmed.ncbi.nlm.nih.gov
… 1 , A Couvineau, P Gaudin, JJ Maoret, C Rouyer-Fessard, P Nicole …
Discovery of a functional immunoreceptor tyrosine‐based switch motif in a 7‐transmembrane‐spanning receptor: role in the orexin receptor OX1R‐driven apoptosis
A El Firar, T Voisin, C Rouyer-Fessard… - The FASEB …, 2009 - Wiley Online Library
The orexin neuropeptides promote ro‐ bust apoptosis in cancer cells. We have recently shown
that the 7‐transmembrane‐spanning orexin receptor OX1R mediates apoptosis through …
that the 7‐transmembrane‐spanning orexin receptor OX1R mediates apoptosis through …
A hallmark of immunoreceptor, the tyrosine‐based inhibitory motif ITIM, is present in the G protein‐coupled receptor OX1R for orexins and drives apoptosis: a novel …
T Voisin, AE Firar, C Rouyer‐Fessard… - The FASEB …, 2008 - Wiley Online Library
Orexins acting at the G protein‐coupled receptor (GPCR) OX1R have recently been shown
to promote dramatic apoptosis in cancer cells. We report here that orexin‐induced apoptosis …
to promote dramatic apoptosis in cancer cells. We report here that orexin‐induced apoptosis …
Interaction of GRF with VIP receptors and stimulation of adenylate cyclase in rat and human intestinal epithelial membranes: Comparison with PHI and secretin
M Laburthe, B Amiranoff, N Boige, C Rouyer-Fessard… - FEBS letters, 1983 - Elsevier
GRF (10 −8 –10 −5 M) is shown to inhibit competitively the binding of [ 125 I]VIP to human
and rat intestinal epithelial membranes. The affinity of GRF for VIP receptor is 700–800-times …
and rat intestinal epithelial membranes. The affinity of GRF for VIP receptor is 700–800-times …