CKD is a significant health concern with an underlying genetic component. Multiple genome–wide
association studies (GWASs) strongly associated CKD with the shroom family …

Chronic kidney disease (CKD) patients are commonly treated with vitamin D analogs, such
as calcitriol. Recent epidemiologic evidence revealed a significant interaction between …

Aims Non-renal extravasation of phosphate from the circulation and transient accumulation
into tissues and extracellular fluid is a regulated process of acute phosphate homeostasis …

The mammalian kidney undergoes cell interactions between the epithelium and mesenchyme
to form the essential filtration unit of the kidney, termed the nephron. A third cell type, the …

Renal dysplasia, a developmental disorder characterized by defective ureteric branching
morphogenesis and nephrogenesis, ranks as one of the major causes of renal failure among …

Schimke immuno-osseous dysplasia (SIOD) is a pleiotropic disorder caused by mutations in
the SWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, subfamily …

Pathogenic accumulation of calcium (Ca) and phosphate (PO 4 ) in vasculature is a sentinel
of advancing cardiovascular disease in chronic kidney disease (CKD). This study sought to …

Vitamin D receptor agonist (VDRA) therapy for PTH suppression is a mainstay for patients
with severe CKD. Calcitriol (1,25‐(OH) 2 D 3 ) is a former first‐line VDRA in CKD treatment. …

The mineral‐bone axis is tightly regulated and dependent on renal function. In chronic kidney
disease (CKD) progressive loss of renal capacity disrupts this axis over‐time, with marked …

Background Non-renal extravasation of phosphate from the circulation and transient
accumulation into tissues and extracellular fluid is a regulated process of acute phosphate …