Angiogenesis, the formation of new capillary blood vessels, is essential not only for the growth
and metastasis of solid tumors, but also for wound and ulcer healing, because without the …

1 In the stomach, prostaglandins protect the gastric mucosa against injuries. One rate‐limiting
step in prostaglandin synthesis is mediated by prostaglandin endoperoxide synthase (…

This study compares the involvement of ATP-sensitive potassium (K ATP ) channels and
prostaglandins in various forms of gastroprotection in the rat. Instillation of 1 ml of 70% ethanol …

The concept that gastroprotection by agents such as mild irritants, antacids, or sucralfate is
prostaglandin (PG)-mediated has been challenged recently. These agents do not …

A complex system of interacting mediators exists in the gastric mucosa to strengthen its
resistance against injury. In this system prostaglandins play an important role. Prostaglandin …

The incorporation of ω-3 and ω-6 fatty acids (FAs) into leukocyte membranes and the
leukotriene (LT)B 4 -, LTB 5 -, LTC 4 -, and LTC 5 -synthesizing capacity in stimulated leukocytes …

Background: Capsaicin-sensitive neurons contain various peptides including calcitonin
gene-related peptide. This study examines (1) whether calcitonin generelated peptide is …

Effects of the cyclo‐oxygenase (COX)‐1 inhibitor SC‐560 and the COX‐2 inhibitors rofecoxib
and DFU were investigated in the normal stomach and after acid challenge. In healthy rats, …

Effects of indomethacin, the selective cyclo‐oxygenase (COX)‐2 inhibitors NS‐398 and DFU,
and dexamethasone on gastric damage induced by 30 min ischaemia followed by 60 min …

Indomethacin delays healing of experimental gastric ulcers. We investigated whether inhibition
of gastric acid secretion by omeprazole or stimulation of angiogenesis by basic fibroblast …