N-((1S)-1-{[4-((2S)-2-{[(2, 4-dichlorophenyl) sulfonyl] amino}-3-hydroxypropanoyl)-1-piperazinyl] carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide …
…, ESR Lashinger, E Gordon, L Evans, BA Misajet… - … of Pharmacology and …, 2008 - ASPET
The transient receptor potential (TRP) vanilloid 4 (TRPV4) member of the TRP superfamily
has recently been implicated in numerous physiological processes. In this study, we describe …
has recently been implicated in numerous physiological processes. In this study, we describe …
Enhanced bladder capacity and reduced prostaglandin E2-mediated bladder hyperactivity in EP3 receptor knockout mice
GP McCafferty, BA Misajet, NJ Laping… - American Journal …, 2008 - journals.physiology.org
Nonsteroidal anti-inflammatory cyclooxygenase inhibitors that function to reduce prostaglandin
E 2 (PGE 2 ) production have been widely reported as effective agents in models of …
E 2 (PGE 2 ) production have been widely reported as effective agents in models of …
[PDF][PDF] GSK1016790A, a novel and potent TRPV4 channel agonist induces urinary bladder contraction and hyperactivity: part I
…, EA Gordon, L Evans, BA Misajet… - … of Pharmacology and …, 2008 - researchgate.net
The transient receptor potential vanilloid 4 (TRPV4) member of the TRP superfamily has
recently been implicated in numerous physiological processes. Here we describe a small …
recently been implicated in numerous physiological processes. Here we describe a small …
Influence of genetic background and gender on bladder function in the mouse
LL Cornelissen, B Misajet, DP Brooks, A Hicks - Autonomic Neuroscience, 2008 - Elsevier
Genetically targeted animals are used throughout research to investigate the role genes
play in biological function, including the lower urinary tract. Generation of transgenic mice …
play in biological function, including the lower urinary tract. Generation of transgenic mice …
[BOOK][B] World's greatest dad
B Goldthwait - 2010 - magpictures.com
A thoughtful but outrageous comedy from Bobcat Goldthwait, WORLD’S GREATEST DAD is
a story about a man that learns the things you want most may not be the things that make …
a story about a man that learns the things you want most may not be the things that make …
Cyclooxygenase-2 is expressed in bladder during fetal development and stimulated by outlet obstruction
JM Park, T Yang, LJ Arend, AM Smart… - American Journal …, 1997 - journals.physiology.org
Studies were undertaken to assess expression of inducible cyclooxygenase (COX)-2 in
bladder during fetal development and COX-1 and COX-2 expression after outlet obstruction. …
bladder during fetal development and COX-1 and COX-2 expression after outlet obstruction. …
Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2
EF Fleming, K Athirakul, MI Oliverio… - American Journal …, 1998 - journals.physiology.org
The actions of prostaglandin (PG) E 2 are mediated by four distinct classes of PGE 2 E-prostanoid
(EP) receptors (EP 1 through EP 4 ). However, the in vivo functions of the individual …
(EP) receptors (EP 1 through EP 4 ). However, the in vivo functions of the individual …
Urodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladder
KS Thorneloe, AL Meredith, AM Knorn… - American Journal …, 2005 - journals.physiology.org
Overactive bladder and incontinence are major medical issues, which lack effective therapy.
Previously, we showed (Meredith AL, Thornloe KS, Werner ME, Nelson MT, and Aldrich RW…
Previously, we showed (Meredith AL, Thornloe KS, Werner ME, Nelson MT, and Aldrich RW…
Afferent fibers of the hypogastric nerves are involved in the facilitating effects of chemical bladder irritation in rats
T Mitsui, H Kakizaki, S Matsuura… - Journal of …, 2001 - journals.physiology.org
To evaluate the role of bladder afferent fibers in the hypogastric nerves (HGN) in modulation
of the micturition reflex induced by chemical bladder irritation, voiding behavior, continuous …
of the micturition reflex induced by chemical bladder irritation, voiding behavior, continuous …
Lumped constant for deoxyglucose is decreased when myocardial glucose uptake is enhanced
K Hashimoto, T Nishimura… - American Journal …, 1999 - journals.physiology.org
Quantification of myocardial glucose uptake by positron emission tomography with [ 18 F]fluorodeoxyglucose
(FDG) requires the “lumped constant” (LC), which corrects the difference of …
(FDG) requires the “lumped constant” (LC), which corrects the difference of …