MicroRNAs (miRNAs) are endogenous noncoding RNAs, about 22 nucleotides in length,
that mediate post-transcriptional gene silencing by annealing to inexactly complementary …

Cigarette smoking is a major risk factor for atherosclerosis and other cardiovascular diseases.
Increasing evidence has demonstrated that nicotine impairs the cardiovascular system by …

The microRNAs miR-1 and miR-133 are preferentially expressed in cardiac and skeletal
muscles and have been shown to regulate differentiation and proliferation of these cells. We …

Recent studies have revealed the role of microRNAs (miRNAs) in a variety of basic biological
and pathological processes and the association of miRNA signatures with human diseases…

Background— A characteristic of both clinical and experimental atrial fibrillation (AF) is atrial
electric remodeling associated with profound reduction of L-type Ca 2+ current and …

Atherosclerosis ( AS ) is an inflammatory disease linked to endothelial dysfunction. Melatonin
is reported to possess substantial anti‐inflammatory properties, which has proven to be …

Aims The present study was designed to decipher molecular mechanisms underlying nicotine's
promoting atrial fibrillation (AF) by inducing atrial structural remodelling. Methods and …

Background— Cardiac interstitial fibrosis is a major cause of the deteriorated performance
of the heart in patients with chronic myocardial infarction. MicroRNAs (miRs) have recently …

We have previously found that the ether-a-go-go related gene (ERG), a long QT syndrome
gene encoding a key K + channel (I Kr ) in cardiac cells, is severely depressed in its …

Atrial fibrillation (AF) is a highly prevalent arrhythmia with pronounced morbidity and mortality.
Inward-rectifier K + current (I K1 ) is believed to be an important regulator of reentrant-…