… In this article Brian Meldrum and John Garthwaite review in vivo and in vitro studies of the
cytotoxicity of amino acids and summarize the contribution of such toxicity to acute and chronic …

Glutamate is the principal excitatory neurotransmitter in brain. Our knowledge of the glutamatergic
synapse has advanced enormously in the last 10 years, primarily through application …

BACKGROUND Numerous lines of evidence challenge the traditional interpretations of how
crystals nucleate and grow in synthetic and natural systems. In contrast to the monomer-by-…

Background Recent reports have suggested that the prevalence of autism and related
spectrum disorders (ASDs) is substantially higher than previously recognised. We sought to …

Background Previous studies have shown that carotid endarterectomy in patients with
symptomatic severe carotid stenosis (defined as stenosis of 70 to 99 percent of the luminal …

In rats ischemia of the forebrain induced by a 30-minute occlusion of the carotid artery,
followed by 120 minutes of arterial reperfusion, produced ischemic lesions of selectively …

The unique and frequently beautiful morphologies that characterize many biominerals have
long been a source of fascination. While research began by looking first at individual …

Purpose The frequency of BRCA1 and BRCA2 germ-line mutations in women with ovarian
cancer is unclear; reports vary from 3% to 27%. The impact of germ-line mutation on …

The goal of patient-centered communication (PCC) is to help practitioners provide care that
is concordant with the patient's values, needs and preferences, and that allows patients to …

Knowledge about the role of the right ventricle in health and disease historically has lagged
behind that of the left ventricle. Less muscular, restricted in its role to pumping blood through …