Expression of human immunodeficiency virus type 1 (HIV-1) can be activated in a chronically
infected T-cell line (ACH2 cells) by a cytokine, human tumor necrosis factor alpha (TNF-…

Bone marrow-derived mesenchymal stem cells (MSCs) hold great promise for treating
immune disorders because of their immunoregulatory capacity, but the mechanism remains …

Mesenchymal stem cells (MSCs), also called multipotent mesenchymal stromal cells, exist
in almost all tissues and are a key cell source for tissue repair and regeneration. Under …

The Ah receptor (AhR) mediates many of the toxic responses induced by polyhalogenated
and polycyclic hydrocarbons (PAHs) which are ubiquitous environmental contaminants …

Mesenchymal stromal cells (MSCs) tend to infiltrate into tumors and form a major component
of the tumor microenvironment. These tumor-resident MSCs are known to affect tumor …

It is a long-standing observation that inflammatory responses and infections decrease drug
metabolism capacity in human and experimental animals. Cytochrome P-450 3A4 cyp304 is …

Genomic instability is a hallmark of cancer development and progression, and characterizing
the stresses that create and the mechanisms by which cells respond to genomic …

BACKGROUND Activation of the NF‐κB transcription factor has been previously demonstrated
in two androgen receptor negative prostate cancer cell lines. We wished to extend this …

The NF‐κB family of transcription factors has been shown to be constitutively activated in
various human malignancies, including leukemias, lymphomas, and a number of solid tumors. …

An imbalance between normal adipogenesis and osteogenesis by mesenchymal stem cells
(MSCs) has been shown to be related to various human metabolic diseases, such as …