A phase I evaluation of the pharmacokinetics and tolerability of the HIV-1 maturation inhibitor GSK3640254 and tenofovir alafenamide/emtricitabine in healthy …
…, L Webster, AM Davidson, M Lataillade… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
GSK3640254 is a next-generation maturation inhibitor that would likely be combined with
standard antiretroviral agents to form a regimen of ≥2 fully active classes. This phase I, open-…
standard antiretroviral agents to form a regimen of ≥2 fully active classes. This phase I, open-…
A Phase I, first-in-human, healthy volunteer study to investigate the safety, tolerability, and pharmacokinetics of CVN424, a novel G protein-coupled receptor 6 inverse …
DH Margolin, NL Brice, AM Davidson… - … of Pharmacology and …, 2022 - ASPET
CVN424 is a novel small molecule and first-in-class candidate therapeutic to selectively
modulate GPR6, an orphan G-protein coupled receptor. Expression of GPR6 is largely confined …
modulate GPR6, an orphan G-protein coupled receptor. Expression of GPR6 is largely confined …
Siponimod pharmacokinetics, safety, and tolerability in combination with rifampin, a CYP2C9/3A4 inducer, in healthy subjects
…, S Neelakantham, F Huth, AM Davidson… - European journal of …, 2018 - Springer
… Felix Huth, Antonia M. Davidson, and Eric Legangneux were involved in conceptualising
and designing of studies, and acquisition and analysis of data. All authors made significant …
and designing of studies, and acquisition and analysis of data. All authors made significant …
[HTML][HTML] Severe Vitamin D Deficiency—A Possible Cause of Resistance to Treatment in Psychiatric Pathology
…, MC Manea, CA Ciobanu, DM Petrescu, MO Antonia… - Medicina, 2023 - mdpi.com
In the last few years, vitamin D functions have been studied progressively, and along with
their main role in regulating calcium homeostasis, the potential function in the nervous system …
their main role in regulating calcium homeostasis, the potential function in the nervous system …
[HTML][HTML] Method for estimating three-dimensional knee rotations using two inertial measurement units: Validation with a coordinate measurement machine
Three-dimensional rotations across the human knee serve as important markers of knee health
and performance in multiple contexts including human mobility, worker safety and health, …
and performance in multiple contexts including human mobility, worker safety and health, …
[HTML][HTML] Body-worn IMU array reveals effects of load on performance in an outdoor obstacle course
This study introduces a new method to understand how added load affects human performance
across a broad range of athletic tasks (ten obstacles) embedded in an outdoor obstacle …
across a broad range of athletic tasks (ten obstacles) embedded in an outdoor obstacle …
[HTML][HTML] Estimating stair running performance using inertial sensors
Stair running, both ascending and descending, is a challenging aerobic exercise that many
athletes, recreational runners, and soldiers perform during training. Studying biomechanics …
athletes, recreational runners, and soldiers perform during training. Studying biomechanics …
[HTML][HTML] Quantifying performance on an outdoor agility drill using foot-mounted inertial measurement units
Running agility is required for many sports and other physical tasks that demand rapid changes
in body direction. Quantifying agility skill remains a challenge because measuring rapid …
in body direction. Quantifying agility skill remains a challenge because measuring rapid …
Quantifying warfighter performance during a bounding rush (prone-sprinting-prone) maneuver
A single sacrum mounted inertial measurement unit (IMU) was employed to analyze warfighter
performance on a bounding rush (prone-sprinting-prone) task. Thirty-nine participants (…
performance on a bounding rush (prone-sprinting-prone) task. Thirty-nine participants (…
Individual specialization in diet by a generalist marine predator reflects specialization in foraging behaviour
KJ Woo, KH Elliott, M Davidson… - Journal of Animal …, 2008 - Wiley Online Library
We studied chick diet in a known‐age, sexed population of a long‐lived seabird, the
Brünnich's guillemot (Uria lomvia), over 15 years (N = 136; 1993–2007) and attached time–depth–…
Brünnich's guillemot (Uria lomvia), over 15 years (N = 136; 1993–2007) and attached time–depth–…