Arsenic toxicity is a worldwide health concern as several millions of people are exposed to
this toxicant via drinking water, and exposure affects almost every organ system in the body …

Deficiency in fragile X mental retardation protein (FMRP) results in fragile X syndrome (FXS),
an inherited form of intellectual disability. Despite extensive research, it is unclear how …

The effect of ethanol exposure in vitro on the GABA receptor-operated chloride channel was
evaluated by monitoring 36 Cl − influx in a membrane vesicle suspension (microsacs) …

Fragile X syndrome (FXS), a common inherited form of intellectual disability with learning
deficits, results from a loss of fragile X mental retardation protein (FMRP). Despite extensive …

Background: It has been estimated that approximately 12% of women consume alcohol at
some time during their pregnancy, and as many as 5% of children born in the United States …

Abstract Effects of ethanol and pentobarbital on the GABA receptor-chloride channel complex
were evaluated in mice selected for differential sensitivity to the hypnotic effects of ethanol (…

Background: The incidence of fetal alcohol spectrum disorders is estimated to be as high as
1 in 100 births. Efforts to better understand the basis of prenatal ethanol‐induced …

Prenatal ethanol exposure is associated with an increased incidence of depressive disorders
in patient populations. However, the mechanisms that link prenatal ethanol exposure and …

Background: Prenatal ethanol exposure results in a spectrum of cognitive and behavioral
deficits and affects an estimated thirteen percent of children born in the United States. The …

Most studies on arsenic as a drinking water contaminant have focused on its carcinogenic
potential but a few suggest that arsenic can adversely affect cognitive development. One …