[PDF][PDF] Immune effector mechanisms implicated in atherosclerosis: from mice to humans

P Libby, AH Lichtman, GK Hansson - Immunity, 2013 - cell.com
According to the traditional view, atherosclerosis results from a passive buildup of cholesterol
in the artery wall. Yet, burgeoning evidence implicates inflammation and immune effector …

Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation

…, MCG Marcondes, AM Ward, YK Hahn, AH Lichtman… - Science, 2011 - science.org
Phospholipase A 2 (PLA 2 ) enzymes are considered the primary source of arachidonic acid
for cyclooxygenase (COX)–mediated biosynthesis of prostaglandins. Here, we show that a …

[PDF][PDF] Monocyte-macrophages and T cells in atherosclerosis

I Tabas, AH Lichtman - Immunity, 2017 - cell.com
Atherosclerosis is an arterial disease process characterized by the focal subendothelial
accumulation of apolipoprotein-B-containing lipoproteins, immune and vascular wall cells, and …

[HTML][HTML] Fulminant myocarditis with combination immune checkpoint blockade

…, BA Olenchock, AH Lichtman… - … England Journal of …, 2016 - Mass Medical Soc
<p id="p001">Immune checkpoint inhibitors have improved clinical outcomes associated with
numerous cancers, but high-grade, immune-related adverse events can occur, particularly …

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

…, DK Giang, BR Martin, AH Lichtman - Proceedings of the …, 2001 - National Acad Sciences
The medicinal properties of marijuana have been recognized for centuries, but clinical and
societal acceptance of this drug of abuse as a potential therapeutic agent remains fiercely …

[BOOK][B] Basic immunology: functions and disorders of the immune system

AK Abbas, AH Lichtman, S Pillai - 2014 - books.google.com
Understand all the essential concepts in immunology with Basic Immunology: Functions
and Disorders of the Immune System! This concise, focused text provides you with an up-to-date…

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

…, DE Selley, LH Parsons, AH Lichtman… - Nature chemical …, 2009 - nature.com
… Aron H Lichtman … Cravatt, BF & Lichtman, AH Fatty acid amide hydrolase: an emerging
therapeutic target in the endocannabinoid system. Curr. Opin. … Aron H Lichtman

Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-α and matrix metalloproteinase expression

A Kol, GK Sukhova, AH Lichtman, P Libby - Circulation, 1998 - Am Heart Assoc
Background—Recent evidence has implicated Chlamydia pneumoniae in the aggravation
of atherosclerosis. However, the mechanisms by which this agent affects atherogenesis …

Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells

A Kol, AH Lichtman, RW Finberg, P Libby… - The Journal of …, 2000 - journals.aai.org
Heat shock proteins (HSP), highly conserved across species, are generally viewed as
intracellular proteins thought to serve protective functions against infection and cellular stress. …

[HTML][HTML] Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages

A Kol, T Bourcier, AH Lichtman… - The Journal of clinical …, 1999 - Am Soc Clin Investig
Both chlamydial and human heat shock protein 60s (HSP 60), which colocalize in human
atheroma, may contribute to inflammation during atherogenesis. We tested the hypothesis that …