[HTML][HTML] Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes
The incidence of chronic kidney diseases is increasing worldwide, and these conditions are
emerging as a major public health problem. While genetic factors contribute to susceptibility …
emerging as a major public health problem. While genetic factors contribute to susceptibility …
[HTML][HTML] Immunity, endothelial injury and complement-induced coagulopathy in COVID-19
In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …
[HTML][HTML] Understanding the nature of renal disease progression
Among the several theories on the pathophysiology of progressive nephropathies [1—41,
the most convincing one [1, 2] suggests that the initial reduction in nephron number …
the most convincing one [1, 2] suggests that the initial reduction in nephron number …
Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure
…, D Rottoli, S Angioletti, A Benigni… - Journal of the …, 2004 - journals.lww.com
ABSTRACT. Injury to a target organ can be sensed by bone marrow stem cells that migrate
to the site of damage, undergo differentiation, and promote structural and functional repair. …
to the site of damage, undergo differentiation, and promote structural and functional repair. …
Angiotensin II revisited: new roles in inflammation, immunology and aging
That the renin–angiotensin system (RAS) is involved in regulation of blood pressure,
vasoconstriction, sodium intake and potassium excretion is well established. Studies in the last few …
vasoconstriction, sodium intake and potassium excretion is well established. Studies in the last few …
[HTML][HTML] Disruption of the Ang II type 1 receptor promotes longevity in mice
The renin-angiotensin system plays a role in the etiology of hypertension and the pathophysiology
of cardiac and renal diseases in humans. Ang II is the central product of this system …
of cardiac and renal diseases in humans. Ang II is the central product of this system …
Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice
Transplantation of bone marrow mesenchymal stem cells (BM-MSC) or stromal cells from
rodents has been identified as a strategy for renal repair in experimental models of acute …
rodents has been identified as a strategy for renal repair in experimental models of acute …
Should COVID-19 concern nephrologists? Why and to what extent? The emerging impasse of angiotensin blockade
Here, we review the most recent findings on the effects of SARS-CoV-2 infection on kidney
diseases, including acute kidney injury, and examine the potential effects of ARBs on the …
diseases, including acute kidney injury, and examine the potential effects of ARBs on the …
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for ppregnancy-induced hypertension
There is evidence that aspirin in low doses favorably influences the course of pppregnancy-induced
hypertension, but the mechanism, although assumed to involve suppression of the …
hypertension, but the mechanism, although assumed to involve suppression of the …
Recommendations for biomarker identification and qualification in clinical proteomics
Clinical proteomics has yielded some early positive results—the identification of potential
disease biomarkers—indicating the promise for this analytical approach to improve the current …
disease biomarkers—indicating the promise for this analytical approach to improve the current …