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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2008 1
2009 2
2012 1
2013 3
2014 1
2015 3
2016 2
2018 1
2020 1
2023 4
2024 0

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18 results

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Page 1
Preclinical Profile of BYON3521 Predicts an Effective and Safe MET Antibody-Drug Conjugate.
Groothuis PG, Jacobs DCH, Hermens IAT, Damming D, Berentsen K, Mattaar-Hepp E, Stokman MEM, Boekel TV, Rouwette M, van der Vleuten MAJ, Sesink A, Dijcks FA, Coumans RGE, Schouten J, Glaudemans DH, Wijk DV, Blomenröhr M, Kappers WA, Ubink R, van der Lee MMC, Dokter WHA. Groothuis PG, et al. Among authors: van der lee mmc. Mol Cancer Ther. 2023 Jun 1;22(6):765-777. doi: 10.1158/1535-7163.MCT-22-0596. Mol Cancer Ther. 2023. PMID: 37042205 Free PMC article.
BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells.
van Helden MJ, Zwarthoff SA, Arends RJ, Reinieren-Beeren IMJ, Paradé MCBC, Driessen-Engels L, de Laat-Arts K, Damming D, Santegoeds-Lenssen EWH, van Kuppeveld DWJ, Lodewijks I, Olsman H, Matlung HL, Franke K, Mattaar-Hepp E, Stokman MEM, de Wit B, Glaudemans DHRF, van Wijk DEJW, Joosten-Stoffels L, Schouten J, Boersema PJ, van der Vleuten M, Sanderink JWH, Kappers WA, van den Dobbelsteen D, Timmers M, Ubink R, Rouwendal GJA, Verheijden G, van der Lee MMC, Dokter WHA, van den Berg TK. van Helden MJ, et al. Among authors: van der lee mmc. J Immunother Cancer. 2023 Apr;11(4):e006567. doi: 10.1136/jitc-2022-006567. J Immunother Cancer. 2023. PMID: 37068796 Free PMC article.
Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist.
Karstens WFJ, M B P Menge W, Martens G, Op Het Veld SJN, Th H van Eupen J, Demon M, van Achterberg TAE, Arisse-Thijssen MJ, Santegoeds-Lenssen EWH, van der Lee MMC, Ubink R, Arends RJ, Sesink A, Blomenröhr M, Marco Timmers C. Karstens WFJ, et al. Among authors: van der lee mmc. Bioorg Med Chem. 2023 Apr 15;84:117258. doi: 10.1016/j.bmc.2023.117258. Epub 2023 Mar 23. Bioorg Med Chem. 2023. PMID: 37001244 Free article.
Chemokine cooperativity is caused by competitive glycosaminoglycan binding.
Verkaar F, van Offenbeek J, van der Lee MMC, van Lith LHCJ, Watts AO, Rops ALWMM, Aguilar DC, Ziarek JJ, van der Vlag J, Handel TM, Volkman BF, Proudfoot AEI, Vischer HF, Zaman GJR, Smit MJ. Verkaar F, et al. Among authors: van der lee mmc. J Immunol. 2014 Apr 15;192(8):3908-3914. doi: 10.4049/jimmunol.1302159. Epub 2014 Mar 17. J Immunol. 2014. PMID: 24639348 Free PMC article.
Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes.
Watts AO, van Lipzig MM, Jaeger WC, Seeber RM, van Zwam M, Vinet J, van der Lee MM, Siderius M, Zaman GJ, Boddeke HW, Smit MJ, Pfleger KD, Leurs R, Vischer HF. Watts AO, et al. Among authors: van der lee mm. Br J Pharmacol. 2013 Apr;168(7):1662-74. doi: 10.1111/bph.12064. Br J Pharmacol. 2013. PMID: 23170857 Free PMC article.
A Platform for the Generation of Site-Specific Antibody-Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines.
Coumans RGE, Ariaans GJA, Spijker HJ, Renart Verkerk P, Beusker PH, Kokke BPA, Schouten J, Blomenröhr M, van der Lee MMC, Groothuis PG, Ubink R, Dokter WHA, Timmers CM. Coumans RGE, et al. Among authors: van der lee mmc. Bioconjug Chem. 2020 Sep 16;31(9):2136-2146. doi: 10.1021/acs.bioconjchem.0c00337. Epub 2020 Aug 25. Bioconjug Chem. 2020. PMID: 32697078
Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor.
de Kruijf P, van Heteren J, Lim HD, Conti PG, van der Lee MM, Bosch L, Ho KK, Auld D, Ohlmeyer M, Smit MJ, Wijkmans JC, Zaman GJ, Smit MJ, Leurs R. de Kruijf P, et al. Among authors: van der lee mm. J Pharmacol Exp Ther. 2009 May;329(2):783-90. doi: 10.1124/jpet.108.148387. Epub 2009 Feb 3. J Pharmacol Exp Ther. 2009. PMID: 19190236
Unraveling the Interaction between Carboxylesterase 1c and the Antibody-Drug Conjugate SYD985: Improved Translational PK/PD by Using Ces1c Knockout Mice.
Ubink R, Dirksen EHC, Rouwette M, Bos ES, Janssen I, Egging DF, Loosveld EM, van Achterberg TA, Berentsen K, van der Lee MMC, Bichat F, Raguin O, van der Vleuten MAJ, Groothuis PG, Dokter WHA. Ubink R, et al. Among authors: van der lee mmc. Mol Cancer Ther. 2018 Nov;17(11):2389-2398. doi: 10.1158/1535-7163.MCT-18-0329. Epub 2018 Aug 9. Mol Cancer Ther. 2018. PMID: 30093567
18 results