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Interactive Effects of µ-Opioid and Adrenergic-α 2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine.
Obeng S, Leon F, Patel A, Zuarth Gonzalez JD, Chaves Da Silva L, Restrepo LF, Gamez-Jimenez LR, Ho NP, Guerrero Calvache MP, Pallares VLC, Helmes JA, Shiomitsu SK, Soto PL, McCurdy CR, McMahon LR, Wilkerson JL, Hiranita T. Obeng S, et al. Among authors: zuarth gonzalez jd. J Pharmacol Exp Ther. 2022 Dec;383(3):182-198. doi: 10.1124/jpet.122.001192. Epub 2022 Sep 24. J Pharmacol Exp Ther. 2022. PMID: 36153006 Free PMC article.
Characterization of a Nonselective Opioid Receptor Functional Antagonist: Implications for Development as a Novel Opioid Dependence Medication.
Shahbazi Nia S, Ortiz YT, Zuarth Gonzalez JD, Shamir L, Frimpong-Manson K, Hossain MA, Shahi S, Bandy R, Bhat A, Patel D, Diab H, Thompson J, McMahon LR, Wilkerson JL, German NA. Shahbazi Nia S, et al. Among authors: zuarth gonzalez jd. ACS Pharmacol Transl Sci. 2024 Feb 12;7(3):654-666. doi: 10.1021/acsptsci.3c00262. eCollection 2024 Mar 8. ACS Pharmacol Transl Sci. 2024. PMID: 38481688