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Preclinical pharmacology and pharmacokinetics of AZD3783, a selective 5-hydroxytryptamine 1B receptor antagonist.
J Pharmacol Exp Ther. 2011 Nov;339(2):567-78. doi: 10.1124/jpet.110.174433. Epub 2011 Aug 8.
J Pharmacol Exp Ther. 2011.
PMID: 21825000
Clinical Trial.
De novo design of a picomolar nonbasic 5-HT(1B) receptor antagonist.
Nugiel DA, Krumrine JR, Hill DC, Damewood JR Jr, Bernstein PR, Sobotka-Briner CD, Liu J, Zacco A, Pierson ME.
Nugiel DA, et al. Among authors: sobotka briner cd.
J Med Chem. 2010 Feb 25;53(4):1876-80. doi: 10.1021/jm901200t.
J Med Chem. 2010.
PMID: 20088516
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Linear non-competitive inhibition of solubilized human gamma-secretase by pepstatin A methylester, L685458, sulfonamides, and benzodiazepines.
Tian G, Sobotka-Briner CD, Zysk J, Liu X, Birr C, Sylvester MA, Edwards PD, Scott CD, Greenberg BD.
Tian G, et al. Among authors: sobotka briner cd.
J Biol Chem. 2002 Aug 30;277(35):31499-505. doi: 10.1074/jbc.M112328200. Epub 2002 Jun 18.
J Biol Chem. 2002.
PMID: 12072428
Free article.
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Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Simmons MA, Sobotka-Briner CD, Medd AM.
Simmons MA, et al. Among authors: sobotka briner cd.
Neuroscience. 2008 Oct 28;156(4):987-94. doi: 10.1016/j.neuroscience.2008.08.037. Epub 2008 Aug 23.
Neuroscience. 2008.
PMID: 18801417
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