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Year | Number of Results |
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1997 | 2 |
2001 | 1 |
2002 | 1 |
2004 | 1 |
2015 | 1 |
2024 | 0 |
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Page 1
VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent.
J Pharm Sci. 2001 May;90(5):625-37. doi: 10.1002/1520-6017(200105)90:5<625::aid-jps1019>3.0.co;2-1.
J Pharm Sci. 2001.
PMID: 11288107
VX-509 (decernotinib) is a potent and selective janus kinase 3 inhibitor that attenuates inflammation in animal models of autoimmune disease.
Mahajan S, Hogan JK, Shlyakhter D, Oh L, Salituro FG, Farmer L, Hoock TC.
Mahajan S, et al. Among authors: shlyakhter d.
J Pharmacol Exp Ther. 2015 May;353(2):405-14. doi: 10.1124/jpet.114.221176. Epub 2015 Mar 11.
J Pharmacol Exp Ther. 2015.
PMID: 25762693
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Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes.
Jain J, Almquist SJ, Ford PJ, Shlyakhter D, Wang Y, Nimmesgern E, Germann UA.
Jain J, et al. Among authors: shlyakhter d.
Biochem Pharmacol. 2004 Feb 15;67(4):767-76. doi: 10.1016/j.bcp.2003.09.043.
Biochem Pharmacol. 2004.
PMID: 14757177
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Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor.
Jain J, Almquist SJ, Heiser AD, Shlyakhter D, Leon E, Memmott C, Moody CS, Nimmesgern E, Decker C.
Jain J, et al. Among authors: shlyakhter d.
J Pharmacol Exp Ther. 2002 Sep;302(3):1272-7. doi: 10.1124/jpet.102.035659.
J Pharmacol Exp Ther. 2002.
PMID: 12183689
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Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP.
Germann UA, Ford PJ, Shlyakhter D, Mason VS, Harding MW.
Germann UA, et al. Among authors: shlyakhter d.
Anticancer Drugs. 1997 Feb;8(2):141-55. doi: 10.1097/00001813-199702000-00005.
Anticancer Drugs. 1997.
PMID: 9073310
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Cellular and biochemical characterization of VX-710 as a chemosensitizer: reversal of P-glycoprotein-mediated multidrug resistance in vitro.
Germann UA, Shlyakhter D, Mason VS, Zelle RE, Duffy JP, Galullo V, Armistead DM, Saunders JO, Boger J, Harding MW.
Germann UA, et al. Among authors: shlyakhter d.
Anticancer Drugs. 1997 Feb;8(2):125-40. doi: 10.1097/00001813-199702000-00004.
Anticancer Drugs. 1997.
PMID: 9073309
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