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Page 1
An Integrative Approach for Improved Assessment of Cardiovascular Safety Data.
J Pharmacol Exp Ther. 2021 May;377(2):218-231. doi: 10.1124/jpet.120.000348. Epub 2021 Mar 1.
J Pharmacol Exp Ther. 2021.
PMID: 33648939
An integrative pharmacokinetic-cardiovascular physiology modelling approach based on in vivo dog studies including five reference compounds.
Wallman M, Borghardt JM, Martel E, Pairet N, Markert M, Jirstrand M.
Wallman M, et al. Among authors: pairet n.
J Pharmacol Toxicol Methods. 2022 May-Jun;115:107171. doi: 10.1016/j.vascn.2022.107171. Epub 2022 Apr 6.
J Pharmacol Toxicol Methods. 2022.
PMID: 35398273
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TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation.
Pairet N, Mang S, Fois G, Keck M, Kühnbach M, Gindele J, Frick M, Dietl P, Lamb DJ.
Pairet N, et al.
PLoS One. 2018 Apr 17;13(4):e0196055. doi: 10.1371/journal.pone.0196055. eCollection 2018.
PLoS One. 2018.
PMID: 29664963
Free PMC article.
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Importance of the IL-1 Axis in Haemophilus influenzae-stimulated M1 Macrophages Driving Transepithelial Signaling.
Mang S, Braun A, Pairet N, Lamb DJ.
Mang S, et al. Among authors: pairet n.
Am J Respir Cell Mol Biol. 2018 Mar;58(3):412-415. doi: 10.1165/rcmb.2017-0283LE.
Am J Respir Cell Mol Biol. 2018.
PMID: 29493324
No abstract available.
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Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis.
Pairet N, Mang S, Kiechle T, Laufhäger N, Dietl P, Lamb DJ.
Pairet N, et al.
Biochem Biophys Rep. 2019 Sep 19;20:100672. doi: 10.1016/j.bbrep.2019.100672. eCollection 2019 Dec.
Biochem Biophys Rep. 2019.
PMID: 31650038
Free PMC article.
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Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing.
Gindele JA, Mang S, Pairet N, Christ I, Gantner F, Schymeinsky J, Lamb DJ.
Gindele JA, et al. Among authors: pairet n.
PLoS One. 2017 Sep 1;12(9):e0184386. doi: 10.1371/journal.pone.0184386. eCollection 2017.
PLoS One. 2017.
PMID: 28863189
Free PMC article.
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