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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 2
1956 1
1967 4
1968 1
1971 2
1973 2
1974 3
1976 3
1977 4
1979 4
1980 2
1981 2
1982 3
1983 1
1984 2
1985 2
1986 3
1988 5
1989 3
1990 6
1991 1
1992 2
1993 2
1995 1
1996 1
1997 6
1998 3
1999 1
2001 2
2002 2
2003 4
2004 3
2005 2
2006 4
2007 7
2008 4
2009 4
2010 2
2011 2
2012 5
2013 3
2014 1
2015 3
2016 1
2017 2
2018 2
2019 1
2021 6
2022 1
2023 2
2024 1

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129 results

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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Among authors: ogilvie k. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.
Intramolecular Ring-Opening Decomposition of Aryl Azetidines.
Bai G, O'Connell TN, Brodney MA, Butler CR, Czabaniuk LC, Gilbert AM, LaChapelle EA, Li C, McAllister LA, Ogilvie K, Philippe L, Salomon-Ferrer R, Shapiro MJ, Starr JT, Uccello DP, Withka JM, Yan J, Brown MF. Bai G, et al. Among authors: ogilvie k. ACS Med Chem Lett. 2021 Sep 30;12(10):1585-1588. doi: 10.1021/acsmedchemlett.1c00402. eCollection 2021 Oct 14. ACS Med Chem Lett. 2021. PMID: 34676040 Free PMC article.
Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses.
Adams RA, Fernandes-Cerqueira C, Notarnicola A, Mertsching E, Xu Z, Lo WS, Ogilvie K, Chiang KP, Ampudia J, Rosengren S, Cubitt A, King DJ, Mendlein JD, Yang XL, Nangle LA, Lundberg IE, Jakobsson PJ, Schimmel P. Adams RA, et al. Among authors: ogilvie k. Cell Mol Immunol. 2021 Jun;18(6):1463-1475. doi: 10.1038/s41423-019-0331-0. Epub 2019 Dec 4. Cell Mol Immunol. 2021. PMID: 31797905 Free PMC article.
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss.
Garnsey MR, Smith AC, Polivkova J, Arons AL, Bai G, Blakemore C, Boehm M, Buzon LM, Campion SN, Cerny M, Chang SC, Coffman K, Farley KA, Fonseca KR, Ford KK, Garren J, Kong JX, Koos MRM, Kung DW, Lian Y, Li MM, Li Q, Martinez-Alsina LA, O'Connor R, Ogilvie K, Omoto K, Raymer B, Reese MR, Ryder T, Samp L, Stevens KA, Widlicka DW, Yang Q, Zhu K, Fortin JP, Sammons MF. Garnsey MR, et al. Among authors: ogilvie k. J Med Chem. 2023 Mar 9;66(5):3195-3211. doi: 10.1021/acs.jmedchem.2c02012. Epub 2023 Feb 19. J Med Chem. 2023. PMID: 36802610
RAR and RXR modulation in cancer and metabolic disease.
Altucci L, Leibowitz MD, Ogilvie KM, de Lera AR, Gronemeyer H. Altucci L, et al. Among authors: ogilvie km. Nat Rev Drug Discov. 2007 Oct;6(10):793-810. doi: 10.1038/nrd2397. Nat Rev Drug Discov. 2007. PMID: 17906642 Review.
Synthesis of oligoribonucleotides.
Ogilvie KK, Theriault N, Sadana KL. Ogilvie KK, et al. J Am Chem Soc. 1977 Nov 9;99(23):7741-3. doi: 10.1021/ja00465a073. J Am Chem Soc. 1977. PMID: 915168 No abstract available.
Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.
Boras B, Jones RM, Anson BJ, Arenson D, Aschenbrenner L, Bakowski MA, Beutler N, Binder J, Chen E, Eng H, Hammond H, Hammond J, Haupt RE, Hoffman R, Kadar EP, Kania R, Kimoto E, Kirkpatrick MG, Lanyon L, Lendy EK, Lillis JR, Logue J, Luthra SA, Ma C, Mason SW, McGrath ME, Noell S, Obach RS, O'Brien MN, O'Connor R, Ogilvie K, Owen D, Pettersson M, Reese MR, Rogers TF, Rossulek MI, Sathish JG, Shirai N, Steppan C, Ticehurst M, Updyke LW, Weston S, Zhu Y, Wang J, Chatterjee AK, Mesecar AD, Frieman MB, Anderson AS, Allerton C. Boras B, et al. Among authors: ogilvie k. bioRxiv [Preprint]. 2021 Feb 12:2020.09.12.293498. doi: 10.1101/2020.09.12.293498. bioRxiv. 2021. PMID: 32935104 Free PMC article. Updated. Preprint.
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Boras B, Jones RM, Anson BJ, Arenson D, Aschenbrenner L, Bakowski MA, Beutler N, Binder J, Chen E, Eng H, Hammond H, Hammond J, Haupt RE, Hoffman R, Kadar EP, Kania R, Kimoto E, Kirkpatrick MG, Lanyon L, Lendy EK, Lillis JR, Logue J, Luthra SA, Ma C, Mason SW, McGrath ME, Noell S, Obach RS, O' Brien MN, O'Connor R, Ogilvie K, Owen D, Pettersson M, Reese MR, Rogers TF, Rosales R, Rossulek MI, Sathish JG, Shirai N, Steppan C, Ticehurst M, Updyke LW, Weston S, Zhu Y, White KM, García-Sastre A, Wang J, Chatterjee AK, Mesecar AD, Frieman MB, Anderson AS, Allerton C. Boras B, et al. Among authors: ogilvie k. Nat Commun. 2021 Oct 18;12(1):6055. doi: 10.1038/s41467-021-26239-2. Nat Commun. 2021. PMID: 34663813 Free PMC article.
129 results