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Pharmacokinetic and Target Engagement Measures of ANX007, an Anti-C1q Antibody Fragment, Following Intravitreal Administration in Nonhuman Primates.
Grover A, Sankaranarayanan S, Mathur V, Suri P, Qiu H, Andrews-Zwilling Y, Mease K, Taylor LK, Cahir-McFarland E, Keswani S, Yednock T. Grover A, et al. Among authors: mease k. Invest Ophthalmol Vis Sci. 2023 Feb 1;64(2):3. doi: 10.1167/iovs.64.2.3. Invest Ophthalmol Vis Sci. 2023. PMID: 36729444 Free PMC article.
Mechanisms underlying benign and reversible unconjugated hyperbilirubinemia observed with faldaprevir administration in hepatitis C virus patients.
Sane RS, Steinmann GG, Huang Q, Li Y, Podila L, Mease K, Olson S, Taub ME, Stern JO, Nehmiz G, Böcher WO, Asselah T, Tweedie D. Sane RS, et al. Among authors: mease k. J Pharmacol Exp Ther. 2014 Nov;351(2):403-12. doi: 10.1124/jpet.114.218081. Epub 2014 Sep 9. J Pharmacol Exp Ther. 2014. PMID: 25204339 Clinical Trial.
Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.
Taub ME, Mease K, Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, Jani M, Lee CA. Taub ME, et al. Among authors: mease k. Drug Metab Dispos. 2011 Nov;39(11):2093-102. doi: 10.1124/dmd.111.040816. Epub 2011 Aug 17. Drug Metab Dispos. 2011. PMID: 21849517