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Page 1
Substituted 7-amino-5-thio-thiazolo[4,5-d]pyrimidines as potent and selective antagonists of the fractalkine receptor (CX3CR1).
Karlström S, Nordvall G, Sohn D, Hettman A, Turek D, Åhlin K, Kers A, Claesson M, Slivo C, Lo-Alfredsson Y, Petersson C, Bessidskaia G, Svensson PH, Rein T, Jerning E, Malmberg Å, Ahlgen C, Ray C, Vares L, Ivanov V, Johansson R. Karlström S, et al. Among authors: jerning e. J Med Chem. 2013 Apr 25;56(8):3177-90. doi: 10.1021/jm3012273. Epub 2013 Apr 4. J Med Chem. 2013. PMID: 23516963
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418.
Bhat R, Xue Y, Berg S, Hellberg S, Ormö M, Nilsson Y, Radesäter AC, Jerning E, Markgren PO, Borgegård T, Nylöf M, Giménez-Cassina A, Hernández F, Lucas JJ, Díaz-Nido J, Avila J. Bhat R, et al. Among authors: jerning e. J Biol Chem. 2003 Nov 14;278(46):45937-45. doi: 10.1074/jbc.M306268200. Epub 2003 Aug 19. J Biol Chem. 2003. PMID: 12928438 Free article.
Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676.
Varnäs K, Juréus A, Johnström P, Ahlgren C, Schött P, Schou M, Gruber S, Jerning E, Malmborg J, Halldin C, Afzelius L, Farde L. Varnäs K, et al. Among authors: jerning e. J Pharmacol Exp Ther. 2016 Sep;358(3):464-71. doi: 10.1124/jpet.116.234146. Epub 2016 Jul 11. J Pharmacol Exp Ther. 2016. PMID: 27402278
Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
Berg S, Bergh M, Hellberg S, Högdin K, Lo-Alfredsson Y, Söderman P, von Berg S, Weigelt T, Ormö M, Xue Y, Tucker J, Neelissen J, Jerning E, Nilsson Y, Bhat R. Berg S, et al. Among authors: jerning e. J Med Chem. 2012 Nov 8;55(21):9107-19. doi: 10.1021/jm201724m. Epub 2012 Apr 27. J Med Chem. 2012. PMID: 22489897
14 results