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Antiarrhythmic efficacy of selective blockade of the cardiac slowly activating delayed rectifier current, I(Ks), in canine models of malignant ischemic ventricular arrhythmia.
Lynch JJ Jr, Houle MS, Stump GL, Wallace AA, Gilberto DB, Jahansouz H, Smith GR, Tebben AJ, Liverton NJ, Selnick HG, Claremon DA, Billman GE. Lynch JJ Jr, et al. Among authors: houle ms. Circulation. 1999 Nov 2;100(18):1917-22. doi: 10.1161/01.cir.100.18.1917. Circulation. 1999. PMID: 10545437
Effects of a novel cardioselective ATP-sensitive potassium channel antagonist, 1-[[5-[2-(5-chloro-o-anisamido)ethyl]-beta-methoxyethoxyphenyl]sulfonyl]-3-methylthiourea, sodium salt (HMR 1402), on susceptibility to ventricular fibrillation induced by myocardial ischemia: in vitro and in vivo studies.
Billman GE, Houle MS, Englert HC, Gögelein H. Billman GE, et al. Among authors: houle ms. J Pharmacol Exp Ther. 2004 Apr;309(1):182-92. doi: 10.1124/jpet.103.061416. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722326