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The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer Membranes.
Krug U, Gloge A, Schmidt P, Becker-Baldus J, Bernhard F, Kaiser A, Montag C, Gauglitz M, Vishnivetskiy SA, Gurevich VV, Beck-Sickinger AG, Glaubitz C, Huster D. Krug U, et al. Among authors: gloge a. Angew Chem Int Ed Engl. 2020 Dec 21;59(52):23854-23861. doi: 10.1002/anie.202006075. Epub 2020 Sep 30. Angew Chem Int Ed Engl. 2020. PMID: 32790043 Free PMC article.
A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [13C6]-labeled basimglurant in humans.
Guerini E, Schadt S, Greig G, Haas R, Husser C, Zell M, Funk C, Hartung T, Gloge A, Mallalieu NL. Guerini E, et al. Among authors: gloge a. Xenobiotica. 2017 Feb;47(2):144-153. doi: 10.3109/00498254.2016.1169334. Epub 2016 Apr 28. Xenobiotica. 2017. PMID: 27123695
Pharmacology of basimglurant (RO4917523, RG7090), a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depression.
Lindemann L, Porter RH, Scharf SH, Kuennecke B, Bruns A, von Kienlin M, Harrison AC, Paehler A, Funk C, Gloge A, Schneider M, Parrott NJ, Polonchuk L, Niederhauser U, Morairty SR, Kilduff TS, Vieira E, Kolczewski S, Wichmann J, Hartung T, Honer M, Borroni E, Moreau JL, Prinssen E, Spooren W, Wettstein JG, Jaeschke G. Lindemann L, et al. Among authors: gloge a. J Pharmacol Exp Ther. 2015 Apr;353(1):213-33. doi: 10.1124/jpet.114.222463. Epub 2015 Feb 9. J Pharmacol Exp Ther. 2015. PMID: 25665805