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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1977 3
1978 1
1979 1
1980 2
1981 6
1982 9
1983 3
1984 3
1985 4
1986 4
1987 6
1988 5
1989 4
1990 7
1991 2
1992 4
1993 6
1994 3
1995 6
1996 6
1997 3
1998 9
1999 4
2000 14
2001 8
2002 10
2003 9
2004 12
2005 11
2006 15
2007 19
2008 12
2009 13
2010 9
2011 8
2012 9
2013 9
2014 14
2015 2
2016 10
2017 7
2018 10
2019 14
2020 12
2021 11
2022 10
2023 8
2024 5

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334 results

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Page 1
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. Shin HR, et al. Among authors: covey df. Science. 2022 Sep 16;377(6612):1290-1298. doi: 10.1126/science.abg6621. Epub 2022 Aug 25. Science. 2022. PMID: 36007018 Free PMC article.
7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.
Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, Schaefer EL, Ekpo I, Schmitz W, Horling A, Imming P, Miyamoto S, Wehman AM, Genaro-Mattos TC, Mirnics K, Kumar L, Klein-Seetharaman J, Meierjohann S, Weigand I, Kroiss M, Bornkamm GW, Gomes F, Netto LES, Sathian MB, Konrad DB, Covey DF, Michalke B, Bommert K, Bargou RC, Garcia-Saez A, Pratt DA, Fedorova M, Trumpp A, Conrad M, Friedmann Angeli JP. Freitas FP, et al. Among authors: covey df. Nature. 2024 Feb;626(7998):401-410. doi: 10.1038/s41586-023-06878-9. Epub 2024 Jan 31. Nature. 2024. PMID: 38297129
Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.
Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. Castellano BM, et al. Among authors: covey df. Science. 2017 Mar 24;355(6331):1306-1311. doi: 10.1126/science.aag1417. Science. 2017. PMID: 28336668 Free PMC article.
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.
Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Among authors: covey df. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.
Neurosteroid enantiomers as potentially novel neurotherapeutics.
Covey DF, Evers AS, Izumi Y, Maguire JL, Mennerick SJ, Zorumski CF. Covey DF, et al. Neurosci Biobehav Rev. 2023 Jun;149:105191. doi: 10.1016/j.neubiorev.2023.105191. Epub 2023 Apr 20. Neurosci Biobehav Rev. 2023. PMID: 37085023 Free PMC article. Review.
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: covey df. bioRxiv [Preprint]. 2023 May 24:2023.05.23.540554. doi: 10.1101/2023.05.23.540554. bioRxiv. 2023. PMID: 37292845 Free PMC article. Updated. Preprint.
A novel mechanism of non-feminizing estrogens in neuroprotection.
Engler-Chiurazzi EB, Covey DF, Simpkins JW. Engler-Chiurazzi EB, et al. Among authors: covey df. Exp Gerontol. 2017 Aug;94:99-102. doi: 10.1016/j.exger.2016.10.013. Epub 2016 Nov 3. Exp Gerontol. 2017. PMID: 27818250 Free PMC article. Review.
Neurosteroids, stress and depression: potential therapeutic opportunities.
Zorumski CF, Paul SM, Izumi Y, Covey DF, Mennerick S. Zorumski CF, et al. Among authors: covey df. Neurosci Biobehav Rev. 2013 Jan;37(1):109-22. doi: 10.1016/j.neubiorev.2012.10.005. Epub 2012 Oct 17. Neurosci Biobehav Rev. 2013. PMID: 23085210 Free PMC article. Review.
Synthesis of ent-25-hydroxycholesterol.
Westover EJ, Covey DF. Westover EJ, et al. Among authors: covey df. Steroids. 2006 Jun;71(6):484-8. doi: 10.1016/j.steroids.2006.01.007. Epub 2006 Mar 6. Steroids. 2006. PMID: 16519912
334 results