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Year Number of Results
2003 1
2004 2
2005 1
2006 2
2007 5
2008 2
2012 1
2024 0

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Page 1
2-(N-Benzyl-N-phenylsulfonamido)alkyl amide derivatives as γ-secretase inhibitors.
Parker MF, Barten DM, Bergstrom CP, Bronson JJ, Corsa JA, Dee MF, Gai Y, Guss VL, Higgins MA, Keavy DJ, Loo A, Mate RA, Marcin LR, McElhone KE, Polson CT, Roberts SB, Macor JE. Parker MF, et al. Among authors: corsa ja. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6828-31. doi: 10.1016/j.bmcl.2012.09.057. Epub 2012 Sep 24. Bioorg Med Chem Lett. 2012. PMID: 23046960
Amino-caprolactam derivatives as gamma-secretase inhibitors.
Parker MF, Bronson JJ, Barten DM, Corsa JA, Du W, Felsenstein KM, Guss VL, Izzarelli D, Loo A, McElhone KE, Marcin LR, Padmanabha R, Pak R, Polson CT, Toyn JH, Varma S, Wang J, Wong V, Zheng M, Roberts SB. Parker MF, et al. Among authors: corsa ja. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5790-5. doi: 10.1016/j.bmcl.2007.08.047. Epub 2007 Aug 26. Bioorg Med Chem Lett. 2007. PMID: 17869509
Carbamate-appended N-alkylsulfonamides as inhibitors of gamma-secretase.
Bergstrom CP, Sloan CP, Lau WY, Smith DW, Zheng M, Hansel SB, Polson CT, Corsa JA, Barten DM, Felsenstein KM, Roberts SB. Bergstrom CP, et al. Among authors: corsa ja. Bioorg Med Chem Lett. 2008 Jan 15;18(2):464-8. doi: 10.1016/j.bmcl.2007.11.102. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18178084
Nitrogen-appended N-alkylsulfonamides as inhibitors of gamma-secretase.
Bergstrom CP, Sloan CP, Wang HH, Parker MF, Smith DW, Zheng M, Hansel SB, Polson CT, Barber LE, Bursuker I, Guss VL, Corsa JA, Barten DM, Felsenstein KM, Roberts SB. Bergstrom CP, et al. Among authors: corsa ja. Bioorg Med Chem Lett. 2008 Jan 1;18(1):175-8. doi: 10.1016/j.bmcl.2007.10.105. Epub 2007 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18023581
2,3-Benzodiazepin-1,4-diones as peptidomimetic inhibitors of gamma-secretase.
Prasad CV, Vig S, Smith DW, Gao Q, Polson CT, Corsa JA, Guss VL, Loo A, Barten DM, Zheng M, Felsenstein KM, Roberts SB. Prasad CV, et al. Among authors: corsa ja. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3535-8. doi: 10.1016/j.bmcl.2004.04.056. Bioorg Med Chem Lett. 2004. PMID: 15177468
N-(5-chloro-2-(hydroxymethyl)-N-alkyl-arylsulfonamides as gamma-secretase inhibitors.
Parker MF, Barten DM, Bergstrom CP, Bronson JJ, Corsa JA, Deshpande MS, Felsenstein KM, Guss VL, Hansel SB, Johnson G, Keavy DJ, Lau WY, Mock J, Prasad CV, Polson CT, Sloan CP, Smith DW, Wallace OB, Wang HH, Williams A, Zheng M. Parker MF, et al. Among authors: corsa ja. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4432-6. doi: 10.1016/j.bmcl.2007.06.022. Epub 2007 Jun 10. Bioorg Med Chem Lett. 2007. PMID: 17606371
Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.
Barten DM, Guss VL, Corsa JA, Loo A, Hansel SB, Zheng M, Munoz B, Srinivasan K, Wang B, Robertson BJ, Polson CT, Wang J, Roberts SB, Hendrick JP, Anderson JJ, Loy JK, Denton R, Verdoorn TA, Smith DW, Felsenstein KM. Barten DM, et al. Among authors: corsa ja. J Pharmacol Exp Ther. 2005 Feb;312(2):635-43. doi: 10.1124/jpet.104.075408. Epub 2004 Sep 27. J Pharmacol Exp Ther. 2005. PMID: 15452193
Donepezil primarily attenuates scopolamine-induced deficits in psychomotor function, with moderate effects on simple conditioning and attention, and small effects on working memory and spatial mapping.
Lindner MD, Hogan JB, Hodges DB Jr, Orie AF, Chen P, Corsa JA, Leet JE, Gillman KW, Rose GM, Jones KM, Gribkoff VK. Lindner MD, et al. Among authors: corsa ja. Psychopharmacology (Berl). 2006 Nov;188(4):629-40. doi: 10.1007/s00213-006-0556-3. Epub 2006 Sep 27. Psychopharmacology (Berl). 2006. PMID: 17004085
Soluble Abeta and cognitive function in aged F-344 rats and Tg2576 mice.
Lindner MD, Hogan JB, Krause RG, Machet F, Bourin C, Hodges DB Jr, Corsa JA, Barten DM, Toyn JH, Stock DA, Rose GM, Gribkoff VK. Lindner MD, et al. Among authors: corsa ja. Behav Brain Res. 2006 Oct 2;173(1):62-75. doi: 10.1016/j.bbr.2006.06.003. Epub 2006 Jul 7. Behav Brain Res. 2006. PMID: 16828889
11 results