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2000 1
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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.
Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, Cragg S, Dehay B, Bitan G, Matute C, Bezard E, Wade-Martins R. Bengoa-Vergniory N, et al. Among authors: cioroch m. Nat Commun. 2020 Sep 28;11(1):4885. doi: 10.1038/s41467-020-18689-x. Nat Commun. 2020. PMID: 32985503 Free PMC article.
REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model.
Ryan BJ, Bengoa-Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, Sloan M, Saqlain S, Cherubini M, Poppinga J, Bogtofte H, Cioroch M, Hester S, Wade-Martins R. Ryan BJ, et al. Among authors: cioroch m. J Neurosci. 2021 Apr 21;41(16):3731-3746. doi: 10.1523/JNEUROSCI.1478-20.2021. Epub 2021 Feb 9. J Neurosci. 2021. PMID: 33563726 Free PMC article.
The cytotoxic effect of purine riboside on COS-7 cells.
Tkacz K, Cioroch M, Skladanowski AC, Makarewicz W. Tkacz K, et al. Among authors: cioroch m. Adv Exp Med Biol. 2000;486:355-9. doi: 10.1007/0-306-46843-3_68. Adv Exp Med Biol. 2000. PMID: 11783515 No abstract available.
LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.
Sloan M, Alegre-Abarrategui J, Potgieter D, Kaufmann AK, Exley R, Deltheil T, Threlfell S, Connor-Robson N, Brimblecombe K, Wallings R, Cioroch M, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, Dodson PD, Wade-Martins R. Sloan M, et al. Among authors: cioroch m. Hum Mol Genet. 2016 Mar 1;25(5):951-63. doi: 10.1093/hmg/ddv628. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744332 Free PMC article.
Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model.
Janezic S, Threlfell S, Dodson PD, Dowie MJ, Taylor TN, Potgieter D, Parkkinen L, Senior SL, Anwar S, Ryan B, Deltheil T, Kosillo P, Cioroch M, Wagner K, Ansorge O, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, Wade-Martins R. Janezic S, et al. Among authors: cioroch m. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4016-25. doi: 10.1073/pnas.1309143110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082145 Free PMC article.
A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor.
Kerr AG, Tam LCS, Hale AB, Cioroch M, Douglas G, Agkatsev S, Hibbitt O, Mason J, Holt-Martyn J, Bataille CJR, Wynne GM, Channon KM, Russell AJ, Wade-Martins R. Kerr AG, et al. Among authors: cioroch m. J Pharmacol Exp Ther. 2017 Jun;361(3):417-428. doi: 10.1124/jpet.116.239574. Epub 2017 Mar 30. J Pharmacol Exp Ther. 2017. PMID: 28360334 Free PMC article.
12 results