Abstract
With the advent of the first generation of both selective and nonselective endothelin antagonists being a relatively recent event, the manifold therapeutic potentials of these compounds are only now being explored clinically. Undoubtedly, numerous clinical utilities for these compounds will soon be realized.
MeSH terms
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Cardiovascular Diseases / drug therapy
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Endothelin Receptor Antagonists
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Endothelins / antagonists & inhibitors*
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Endothelins / classification
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Endothelins / genetics
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Endothelins / metabolism
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Endothelins / therapeutic use
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Humans
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Molecular Biology
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Receptors, Endothelin / classification
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Receptors, Endothelin / genetics
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Receptors, Endothelin / metabolism
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Signal Transduction
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Tissue Distribution
Substances
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Endothelin Receptor Antagonists
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Endothelins
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Receptors, Endothelin