Biological effects of folic acid antagonists with antineoplastic activity

Pharmacol Ther. 1984;25(1):61-82. doi: 10.1016/0163-7258(84)90024-x.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Marrow / drug effects
  • Cell Cycle / drug effects
  • Flow Cytometry
  • Folic Acid Antagonists / pharmacology*
  • Folic Acid Antagonists / therapeutic use
  • Humans
  • Leukemia / drug therapy
  • Methotrexate / pharmacology*
  • Methotrexate / therapeutic use
  • Neoplasms / drug therapy
  • Structure-Activity Relationship
  • Thymidylate Synthase / antagonists & inhibitors
  • Tritium

Substances

  • Folic Acid Antagonists
  • Tritium
  • Thymidylate Synthase
  • Methotrexate