Abstract
Nicotine is the primary reason why people consume tobacco products and it may contribute to causation of tobacco-related diseases. This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Brain / drug effects
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Cardiovascular Diseases / etiology
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Cardiovascular System / drug effects
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Chewing Gum
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Endocrine Glands / drug effects
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Humans
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Lung Diseases / etiology
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Mice
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Muscles / drug effects
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Neoplasms, Experimental / etiology
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Nervous System / drug effects
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Nicotine / adverse effects
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Nicotine / metabolism
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Nicotine / pharmacology*
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Nicotine / therapeutic use
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Peptic Ulcer / etiology
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Risk
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Skin Neoplasms / etiology
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Smoking
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Tobacco Use Disorder / prevention & control